Letter to the Editor
On Omeprazole and Iron Replacement
Abstract
I read with great interest the article1 entitled “Effect of Omeprazole on Oral Iron Replacement in Patients With Iron Deficiency Anemia.” The authors declared that the patients presented here are the first of their kind to be reported. However, this relation has been well known for a long time and is expressed in classical textbooks such as Rudolph's Pediatrics2 and Hematology of Infancy and Childhood.3 Fortunately, the use of proton pump inhibitors is seldom necessary in pediatric patients, since peptic ulcer disease is rare in children. Therefore, treatment with these drugs (and their attendant complications) is relatively uncommon in children. Widespread use of these drugs in adults should probably cause more complications than seen in children.This content is limited to qualifying members.
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References
1. Sharma VR, Brannon MA, Carloss EA. Effect of omeprazole on oral iron replacement in patients with iron deficiency anemia. South Med J 2004;97:887–889.
2. Bridges KR, Pearson HA. Nutritional anemias: iron deficiency, in Rudolph CD, Rudolph AM (eds):Rudolph's Pediatrics. New York, McGraw-Hill, 21st edition, 2002, pp 1525–1528.
3. Andrews NC. Disorders of iron metabolism and sideroblastic anemia: iron deficiency, in Nathan DG, Orkin SH, Ginsburg D, Look AT (eds): Nathan and Oski's Hematology of Infancy and Childhood. Philadelphia, Saunders, 6th edition, 2003, pp 470–471.
