Perspectives

Optimal Treatment for Patients with Heart Failure with Preserved Ejection Fraction

Authors: Nicole Northcutt, PharmD, Christopher Jackson, MD

Abstract

In light of recent studies, how can providers approach and offer optimal care to patients with heart failure with preserved ejection fraction (HFpEF)? As evidenced by years of research, there is clear guidance to treat patients with heart failure with reduced ejection fraction (HFrEF). The data model the benefits of treatment to reduce hospitalizations, improve symptoms, and reduce morbidity and mortality. Data in patients with HFpEF have remained limited, however. Although there has not been statistically significant clinical evidence to support morbidity and mortality benefit in patients with HFpEF, newer evidence with certain pharmacologic therapies show benefit in reducing hospitalizations in HFpEF patients.

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References

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