Letter to the Editor

Pleural Effusion Heralds Acute Leukemic Transformation of Chronic Myelomonocytic Leukemia

Authors: Chun-Ta Huang, MD, Ping-Hung Kuo, MD, Ming Yao, MD, Yi-Ju Tsai, PhD, Pan-Chyr Yang, MD, PhD

Abstract

To the Editor:


Chronic myelomonocytic leukemia (CMMoL) is a myelodysplastic/myeloproliferative disease characterized by peripheral monocytosis exceeding 1 × 109/L, peripheral and bone marrow blast percentages less than 20%, and absence of a Philadelphia chromosome. Pleural effusion (PE) secondary to CMMoL is uncommon. We report a patient with CMMoL who developed PE as the first manifestation of transformation into acute myelocytic leukemia (AML).

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References

1. Bourantas KL, Tsiara S, Panteli A, et al. Pleural effusion in chronic myelomonocytic leukemia. Acta Haematol 1998;99:34–37.
 
2. Duguid JK, Mackie MJ, McVerry BA. Skin infiltration associated with chronic myelomonocytic leukaemia. Br J Haematol 1983;53:257–264.
 
3. Manoharan A. Malignant pleural effusion in chronic myelomonocytic leukaemia. Thorax 1991;46:461–462.