Case Report

Primary Non-Hodgkin Lymphoma of the Larynx

Authors: Bernardino Roca, MD, PhD, Barbara Vidal-Tegedor, MD, Magin Moya, MD

Abstract

A rare case of primary large B-cell non-Hodgkin lymphoma of the larynx is reported. The patient was an 80-year-old female who presented with pharyngeal discomfort and dysphagia. Radiotherapy was instituted with complete remission of the tumor. Nine months afterward, she presented with aspiration pneumonia and dysphagia. Indirect laryngoscopy disclosed laryngeal and esophageal edema, which was probably related to radiotherapy. No signs of tumor recurrence were observed. Three months later, she was entirely asymptomatic. Although cases of aggressive course and poor response to therapy exist, primary large B-cell non-Hodgkin lymphoma of the larynx is generally considered a relatively benign and radiosensitive tumor.


Key Points


* Primary large B-cell non-Hodgkin lymphoma of the larynx accounts for less than 1% of laryngeal neoplasms.


* The tumor is generally considered relatively benign.


* Radiation therapy is effective and considered treatment of choice in that neoplasm.

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