Abstract
Abstract:Splenic metastases from solid tumors are uncommon. They may be observed in a context of multivisceral dissemination or as a solitary lesion. We report the case of an 80-year-old woman with a history of two metachronous gastric cancers treated with distal gastrectomy and resection of the gastric remnant within a period of 15 years, who presented with a huge splenic tumor mass three years after the second operation. Splenectomy was performed. The resection specimens showed a well-circumscribed solid lesion measuring 15 cm in the largest diameter. Histology revealed metastatic gastric cancer. The differential diagnosis and clinical significance of this rare condition is discussed.
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References
References1. Compérat E, Bardier-Dupas A, Camparo P, et al. Splenic metastases: clinicopathologic presentation, differential diagnosis, and pathogenesis. Arch Pathol Lab Med 2007;131:965–969.CompératE]]Bardier-DupasA]]CamparoP&etal;Splenic metastases: clinicopathologic presentation, differential diagnosis, and pathogenesis.Arch Pathol Lab Med2007131965-9692. Lam KY, Tang V. Metastatic tumors to the spleen: a 25-year clinicopathologic study. Arch Pathol Lab Med 2000;124:526–530.LamKY]]TangVMetastatic tumors to the spleen: a 25-year clinicopathologic study.Arch Pathol Lab Med2000124526-5303. Klein B, Stein M, Kuten A, et al. Splenomegaly and solitary spleen metastasis in solid tumors. Cancer 1987;60:100–102.KleinB]]SteinM]]KutenA&etal;Splenomegaly and solitary spleen metastasis in solid tumors.Cancer198760100-1024. Morgenstern L, Rosenberg J, Geller SA. Tumors of the spleen. World J Surg 1985;9:468–476.MorgensternL]]RosenbergJ]]GellerSATumors of the spleen.World J Surg19859468-4765. Kutok JL, Fletcher CD. Splenic vascular tumors. Semin Diagn Pathol 2003;20:128–139.KutokJL]]FletcherCDSplenic vascular tumors.Semin Diagn Pathol200320128-1396. Mollejo M, Algara P, Mateo MS, et al. Large B-cell lymphoma presenting in the spleen: identification of different clinicopathologic conditions. Am J Surg Pathol 2003;27:895–902.MollejoM]]AlgaraP]]MateoMS&etal;Large B-cell lymphoma presenting in the spleen: identification of different clinicopathologic conditions.Am J Surg Pathol200327895-9027. Williams L, Kumar A, Aggarwal S. Calcified splenic metastasis from gastric carcinoma. Abdom Imaging 1995;20:312–314.WilliamsL]]KumarA]]AggarwalSCalcified splenic metastasis from gastric carcinoma.Abdom Imaging199520312-3148. Opocher E, Santambrogio R, Bianchi P, et al. Isolated splenic metastasis from gastric carcinoma: value of CEA and CA 19–9 in early diagnosis: report of two cases. Am J Clin Oncol 2000;23:579–580.OpocherE]]SantambrogioR]]BianchiP&etal;Isolated splenic metastasis from gastric carcinoma: value of CEA and CA 19–9 in early diagnosis: report of two cases.Am J Clin Oncol200023579-5809. Yamanouchi K, Ikematsu Y, Waki S, et al. Solitary splenic metastasis from gastric cancer: report of a case. Surg Today 2002;32:1081–1084.YamanouchiK]]IkematsuY]]WakiS&etal;Solitary splenic metastasis from gastric cancer: report of a case.Surg Today2002321081-1084
