Case Report

Spontaneous Renal Artery Thrombosis and Common Iliac Artery Dissection in a Previously Healthy Young Adult

Authors: D Eli Penn, MD, Amber Gist, MD, Cd, R Neal Axon, MD

Abstract

A previously healthy 20-year-old male with a history of easy bruising presented to the emergency department complaining of intermittent left lower quadrant abdominal pain for one week. He was diagnosed with vascular (type IV) Ehlers-Danlos syndrome (EDS) and attendant defects in type III collagen leading to spontaneous left renal artery thrombosis and common iliac artery dissection. Treatment was conservative. The types of EDS and their general management are discussed.

This content is limited to qualifying members.

Existing members, please login first

If you have an existing account please login now to access this article or view purchase options.

Purchase only this article ($25)

Create a free account, then purchase this article to download or access it online for 24 hours.

Purchase an SMJ online subscription ($75)

Create a free account, then purchase a subscription to get complete access to all articles for a full year.

Purchase a membership plan (fees vary)

Premium members can access all articles plus recieve many more benefits. View all membership plans and benefit packages.

References

1. Prockop DJ, Kuivaniemi H, Tromp G. Heritable disorders of connective tissue, in Fauci AS, Braunwald E, Kasper DL, et al (eds): Harrison's Principles of Internal Medicine. New York, McGraw-Hill, 2007, ed 17.
 
2. Beighton P, De Paepe A, Steinmann B, et al. Ehlers-Danlos syndromes: revised nosology, Villefranche, 1997. Ehlers-Danlos National Foundation (USA) and Ehlers-Danlos Support Group (UK).Am J Med Genet 1998;77:31–37.
 
3. Pope FM, Martin GR, Lichtenstein JR, et al. Patients with Ehlers-Danlos syndrome type IV lack type III collagen. Proc Natl Acad Sci USA 1975;72:1314–1316.
 
4. Tonnessen BH, Sternbergh WC III, Mannava K, et al. Endovascular repair of an iliac artery aneurysm in a patient with Ehlers-Danlos syndrome type IV. J Vasc Surg 2007;45:177–179.
 
5. Peaceman AM, Cruikshank DP. Ehlers-Danlos syndrome and pregnancy: association of type IV disease with maternal death. Obstet Gynecol 1987;69(3 pt 2):428–431.
 
6. Rudd NL, Nimrod C, Holbrook KA, et al. Pregnancy complications in type IV Ehlers-Danlos syndrome. Lancet 1983;1:50–53.
 
7. Pepin M, Schwarze U, Superti-Furga A, et al. Clinical and genetic features of Ehlers–Danlos syndrome type IV, the vascular type. N Engl J Med 2000;342:673–680.
 
8. Cikrit DF, Miles JH, Silver D. Spontaneous arterial perforation: the Ehlers-Danlos specter. J Vasc Surg 1987;5:248–255.
 
9. Oderich GS, Panneton JM, Bower TC, et al. The spectrum, management and clinical outcome of Ehlers-Danlos type IV: a 30-year experience. J Vasc Surg 2005;42:98–106.
 
10. Casana R, Nano G, Dalainas I, et al. Endovascular treatment of hepatic artery aneurysm in a patient with Ehlers-Danlos syndrome, case report. Int Angiol 2004;23:291–295.
 
11. Horowitz MB, Purdy PD, Valentine RJ, et al. Remote vascular catastrophes after neurovascular interventional therapy for type 4 Ehlers-Danlos syndrome. AJNR Am J Neuroradiol 2000;21:974–976.
 
12. Yigala A, Tal H, Nurit H, et al. Thromboembolic renal infarction due to a renal artery aneurysm in a patient with Ehlers-Danlos syndrome type IV. Eur J Intern Med 2006;17:377–379.