Objectives: There is a lack of updated information on premature death and years of potential life lost (YPLL) among human immunodeficiency (HIV)–positive women with cervical cancer. We hypothesize that increased access to preventive resources such as antiretroviral therapy, preexposure prophylaxis, and human papillomavirus vaccines has reduced premature mortality and YPLL...
Objectives: The National Lung Screening Trial (NLST) demonstrated a 20% reduction in mortality with low-dose computed tomography (CT) for lung cancer screening (LCS). The NLST found the greatest benefit to LCS for patients who underwent annual screening for a full 3-year follow-up period. The adherence to serial imaging in the...
Objectives: Preoperative chemotherapy produces tumor shrinkage in most patients with locally advanced breast cancer, including some pathological complete responses (pCRs). We attempted this using a much less toxic sequential regimen, given with concurrent bevacizumab. Methods: Patients with locally advanced breast cancer received 3 intravenous doses each of preoperative sequential liposome...
Objectives: Although cancer is seen in every state in the United States, it does not affect every geographic area and population equally. Kentucky has the highest cancer incidence and mortality rates in the country, with an unusually high number of cases localized in its Appalachian region. Risk factors such as...
Objectives: This study aimed to identify small geographic areas where the childhood cancer yearly incidence and late-stage diagnosis rates were disproportionately higher among racial/ethnic minorities (Hispanics and non-Hispanic African Americans) in Texas. Methods: The study examined childhood cancer disparities in Texas from 2005 to 2014, based on geographic location and...
Objectives: Uterine cancer is the nation’s most common gynecologic malignancy, but it is understudied in the geographically and socioeconomically diverse state of Kentucky (KY). Our aim was to assess the frequency, distribution, and survival of uterine corpus malignancies in KY, and specifically the differences between Appalachia (AP) and non-Appalachia (NAP)...
Objectives: The purpose of this study was to investigate the patient population and outcomes of synovial sarcoma at a single institution.Methods: A retrospective review of the medical records of 28 patients with synovial sarcoma diagnosed from 1992 to 2017 was performed. Demographics, staging, disease location, treatment, and response to treatment...
Objectives: The objectives of this study were to identify and assess the factors associated with concurrent carcinoma and recurrence in women with epithelial borderline ovarian tumors.Methods: The cancer and pathology databases at a tertiary care academic cancer center were queried for all borderline ovarian tumors from 2005 to 2015. Cases...
Objective: The understanding of the effects of physical activity on all-cause mortality among cancer survivors is limited. We attempted to draw a relation between physical activity and survival among those with a diagnosis of cancer.Methods: Data from the 2003–2006 National Health and Nutrition Examination Survey was used, with follow-up through...
Objectives: Underserved populations are at risk of low cancer risk awareness. The purpose of this study was to examine cancer risk awareness and lifestyle issues among uninsured primary care patients in the United States. Methods: Data were collected using a self-administered survey from May to July 2017 of adult free...
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