SMJ Article | Original Article

Lung Cancer in Young Adults: A Single-Center Experience

Objective: This single-center retrospective review examines the unique characteristics of young patients (ages 18 to 40 years) who were diagnosed as having non-small-cell lung cancer (NSCLC) at Markey Cancer Center, the only National Cancer Institute–designated cancer center in the state of Kentucky. Methods: This retrospective study examines adult patients with...

Posted in: Lung Cancer – Clinical Presentation & Diagnosis1

SMJ Article | Invited Commentary

Knowing Your Guidelines in 2022

The fast pace of clinical practice guideline publication makes it difficult to keep up with all of the latest advances. Healthcare specialists in the outpatient setting have the unique challenge of rapidly assimilating these guidelines into clinical practice. With the large volume of evidence syntheses coming out, the Southern Medical...

Posted in: Medical Oncology19

SMJ Article | Perspectives

Know Your Guidelines 2022 Series: The ASCO Management of Dyspnea in Advanced Cancer Guideline Review

Dyspnea is a subjective, yet complex experience of breathlessness, even in the absence of overt hypoxia. Although the pathophysiology of dyspnea is not fully understood, abnormalities of sensation in the brainstem, chest wall, and lungs play a role. Because of the limits of objective findings, many clinicians easily overlook this...

Posted in: Medical Oncology19

SMJ Article | Multidisciplinary Clinical Case Study

Fibrin-Associated Diffuse Large B Cell Lymphoma Found on Revision Arthroplasty of the Knee

Fibrin-associated diffuse large B cell lymphoma (FA-DLBCL) is a rare Epstein-Barr viruspositive B cell lymphoma that is nonmass-forming, does not directly produce symptoms, and is incidentally discovered on histological examination of tissues excised for other reasons. Despite overlap in morphologic and immunophenotypic features with aggressive B cell neoplasms, FA-DLBCL shows...

Posted in: Hematology10 Medical Oncology19

SMJ Article | Original Article

OPEN: Initial Institutional Experience with 18F-Fluciclovine PET-CT in Biochemical Recurrence of Prostate Cancer

Objectives: 18F-fluciclovine (fluciclovine) is an amino acid analog approved by the Food and Drug Administration for use as a radiotracer in positron emission tomography (PET) in men with biochemical recurrence of suspected prostate cancer. The purpose of this study was to investigate the initial institutional experience with 18F-fluciclovine in the...

Posted in: Nephrology and Urology7 Urologic Cancer1 Prostate Disorders1

SMJ Article | Original Article

OPEN: Sentinel Lymph Node Sampling in Robot-Assisted Staging of Endometrial Cancer

Objective: Sentinel lymph node (SLN) sampling in endometrial cancer staging has become an acceptable standard. Indocyanine green dye injected into the cervix and detected by near-infrared light is technically simple and sensitive. We aimed to evaluate SLN sampling in robot-assisted surgical staging of endometrial cancer at a university-affiliated teaching hospital....

Posted in: Gynecologic Cancer5

SMJ Article | Original Article

CME Article: Trends in Incidence and Mortality Rates of Uterine Cancer in Kentucky

Objectives: The objective of this analysis was to gauge how the incidence and mortality of uterine cancer in Kentucky have changed from 1995 through 2017. An assessment of the trends in incidence and mortality across different geographic areas and between different races was also performed. Methods: Age-adjusted annual incidence and...

Posted in: Gynecologic Cancer5 Uterine Disorders2

SMJ Article | Original Article

Training Appalachian Kentucky Youth Cancer Advocates

Objectives: Kentucky has the highest cancer incidence and mortality rates in the United States, with the Appalachian region experiencing the highest of those rates. Cancer advocacy, which is defined as providing support to cancer patients and their communities, represents a means of decreasing the cancer cases in Appalachian Kentucky. This...

Posted in: Medical Oncology19

SMJ Article | Original Article

Trends in Premature Deaths among Women Living with HIV/AIDS and Cervical Cancer

Objectives: There is a lack of updated information on premature death and years of potential life lost (YPLL) among human immunodeficiency (HIV)–positive women with cervical cancer. We hypothesize that increased access to preventive resources such as antiretroviral therapy, preexposure prophylaxis, and human papillomavirus vaccines has reduced premature mortality and YPLL...

Posted in: Infectious Disease79 Acquired Immunodeficiency Syndrome (AIDS) And Human Immunodeficiency Virus (HIV) Infection12 Gynecologic Cancer5

SMJ Article | Original Article

CME Article: Factors Affecting Patient Adherence to Lung Cancer Screening

Objectives: The National Lung Screening Trial (NLST) demonstrated a 20% reduction in mortality with low-dose computed tomography (CT) for lung cancer screening (LCS). The NLST found the greatest benefit to LCS for patients who underwent annual screening for a full 3-year follow-up period. The adherence to serial imaging in the...

Posted in: Medical Oncology19

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