SMJ // Medical Oncology

SMJ Article | Letter to the Editor

On “Predictors of Blood Transfusion in Patients Undergoing Cytoreductive Surgeries for Ovarian Malignancy”

To the Editor: We appreciate the work of Pearce et al regarding the predictors of perioperative blood transfusion in patients undergoing cytoreductive surgery for ovarian cancer.1 They found that patients with lower preoperative hemoglobin and higher intraoperative estimated blood loss (EBL) were at greater risk of needing a blood transfusion....

Posted in: Gynecologic Cancer7

SMJ Article | Review Article

Alpelisib-Induced Hyperglycemia in PIK3CA+ Breast Cancer Patients

Alpelisib is a phosphatidylinositol 3-kinase inhibitor approved by the US Food and Drug Administration for the treatment of hormone receptor–positive metastatic breast cancer with PIK3CA (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit α) mutation. In recent years a number of adverse effects have been observed to be associated with this therapy, the most...

Posted in: Breast Cancer3

SMJ Article | Original Article

Incidence Rates and Outcomes of Nodular and Superficial Spreading Melanoma along the Rural-Urban Continuum in Kentucky and Their Relationship to Provider Care Access

Objectives: This study compared incidence rates, stage at presentation, and cause-specific mortality of nodular and superficial spreading melanoma along the rural-urban continuum in Kentucky. We compared resulting patterns in our data with sample demographic and other potential factors, including population by county and primary care provider rate. Methods: Retrospective patient...

Posted in: Skin Cancer1

SMJ Article | Original Article

Cancer Screening Prevalence and Preference among Hospitalized Women With and Without Obesity

Objectives: This study explored the prevalence of nonadherence and preferences for breast cancer (BRC) and colorectal cancer (CRC) screening among hospitalized women with and without obesity who were cancer-free at baseline. In addition, the study evaluated risk factors associated with nonadherence among hospitalized women with obesity. Methods: A prospective interventional...

Posted in: Breast Cancer3

SMJ Article | Original Article

Extended Venous Thromboembolism Prophylaxis after Robotic Staging for Endometrial Cancer

Objectives: Our objectives were to estimate the incidence of venous thromboembolism (VTE) after robotic staging for endometrial cancer and to compare the incidence of VTE in patients who received a single dose of preoperative prophylaxis of enoxaparin with those who received extended postoperative prophylaxis. Methods: This study is a retrospective...

Posted in: Gynecologic Cancer7

SMJ Article | Perspectives

Building Better Patient Care in Mississippi Radiation Oncology: Why Mississippi Needs a Collaborative Quality Initiative

Objectives: Cancer is an insidious and devastating disease that affects many people. Progress in mortality rate has not been realized universally across the United States, and challenges remain in how to best make up the ground that has been lost in these areas, one of which is Mississippi. Radiation therapy...

Posted in: Medical Oncology25

SMJ Article | Original Article

Lung Cancer in Young Adults: A Single-Center Experience

Objective: This single-center retrospective review examines the unique characteristics of young patients (ages 18 to 40 years) who were diagnosed as having non-small-cell lung cancer (NSCLC) at Markey Cancer Center, the only National Cancer Institute–designated cancer center in the state of Kentucky. Methods: This retrospective study examines adult patients with...

Posted in: Lung Cancer – Clinical Presentation & Diagnosis1

SMJ Article | Invited Commentary

Knowing Your Guidelines in 2022

The fast pace of clinical practice guideline publication makes it difficult to keep up with all of the latest advances. Healthcare specialists in the outpatient setting have the unique challenge of rapidly assimilating these guidelines into clinical practice. With the large volume of evidence syntheses coming out, the Southern Medical...

Posted in: Medical Oncology25

SMJ Article | Perspectives

Know Your Guidelines 2022 Series: The ASCO Management of Dyspnea in Advanced Cancer Guideline Review

Dyspnea is a subjective, yet complex experience of breathlessness, even in the absence of overt hypoxia. Although the pathophysiology of dyspnea is not fully understood, abnormalities of sensation in the brainstem, chest wall, and lungs play a role. Because of the limits of objective findings, many clinicians easily overlook this...

Posted in: Medical Oncology25

SMJ Article | Multidisciplinary Clinical Case Study

Fibrin-Associated Diffuse Large B Cell Lymphoma Found on Revision Arthroplasty of the Knee

Fibrin-associated diffuse large B cell lymphoma (FA-DLBCL) is a rare Epstein-Barr viruspositive B cell lymphoma that is nonmass-forming, does not directly produce symptoms, and is incidentally discovered on histological examination of tissues excised for other reasons. Despite overlap in morphologic and immunophenotypic features with aggressive B cell neoplasms, FA-DLBCL shows...

Posted in: Hematology10 Medical Oncology25

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