Abstract
We present the case of a woman with metastatic malignant gastric stromal tumor occurring four years following a partial gastrectomy and distal esophagectomy, which presented as atypical breast mass with synchronous occult gastrointestinal bleeding. A discussion of metastatic pattern is presented, with emphasis placed on the need for continued surveillance after resectional surgery for gastrointestinal stromal tumor (GIST).
This content is limited to qualifying members.
If you have an existing account please login now to access this article or view purchase options.
Create a free account, then purchase this article to download or access it online for 24 hours.
Create a free account, then purchase a subscription to get complete access to all articles for a full year.
References
References 1. Appelman HD, Helwig EB. Gastric epithelioid leiomyoma and leiomyosarcoma (leiomyoblastoma). Cancer 1976; 38: 708–728.AppelmanHD]]HelwigEBGastric epithelioid leiomyoma and leiomyosarcoma (leiomyoblastoma)Cancer197638708 2. Shiu MH, Farr GH, Papachristou DN, Hajdu SI. Myosarcomas of the stomach: Natural history, prognostic factors and management. Cancer 1982; 49: 177–187.ShiuMH]]FarrGH]]PapachristouDN]]HajduSIMyosarcomas of the stomach: Natural history, prognostic factors and managementCancer198249177 3. Enzinger FM, Lattes R, Torloni H. Histological typing of soft tissue tumours (International Classification of Tumours No. 3). Geneva, World Health Organization, 1969. 4. Erlandson RA, Klimstra DS, Woodruff JM. Subclassification of gastrointestinal stromal tumors based on evaluation by electron microscopy and immunohistochemistry. Ultrastruct Pathol 1996; 20: 373–393.ErlandsonRA]]KlimstraDS]]WoodruffJMSubclassification of gastrointestinal stromal tumors based on evaluation by electron microscopy and immunohistochemistryUltrastruct Pathol199620373 5. Appelman HD. Stromal tumors of the esophagus, stomach, and duodenum, in Appelman HD (ed): Pathology of the Esophagus, Stomach, and Duodenum. New York, Churchill Livingstone, 1984, pp 195–242. 6. Appelman HD, Helwig EB. Sarcomas of the stomach. Am J Clin Pathol 1977; 67: 2–10.AppelmanHD]]HelwigEBSarcomas of the stomachAm J Clin Pathol1977672 7. Dougherty MJ, Compton CC, Talbert M, Wood WC. Sarcomas of the gastrointestinal tract: Separation into favorable and unfavorable prognostic groups by mitotic count. Ann Surg 1991; 214: 569–574.DoughertyMJ]]ComptonCC]]TalbertM]]WoodWCSarcomas of the gastrointestinal tract: Separation into favorable and unfavorable prognostic groups by mitotic countAnn Surg1991214569 8. Farrugia G, Kim CH, Grant CS, Zinsmeister AR. Leiomyosarcoma of the stomach: Determinants of long-term survival. Mayo Clin Proc 1992; 67: 533–536.FarrugiaG]]KimCH]]GrantCS]]ZinsmeisterARLeiomyosarcoma of the stomach: Determinants of long-term survivalMayo Clin Proc199267533 9. Ng EH, Pollock RE, Romsdahl MM. Prognostic implications of patterns of failure for gastrointestinal leiomyosarcomas. Cancer 1992; 69: 1334–1341.NgEH]]PollockRE]]RomsdahlMMPrognostic implications of patterns of failure for gastrointestinal leiomyosarcomasCancer1992691334 10. Ranchod M, Kempson RL. Smooth muscle tumors of the gastrointestinal tract and retroperitoneum: A pathologic analysis of 100 cases. Cancer 1977; 39: 255–262.RanchodM]]KempsonRLSmooth muscle tumors of the gastrointestinal tract and retroperitoneum: A pathologic analysis of 100 casesCancer197739255 11. Grant CS, Kim CH, Farrugia G, Zinsmeister A, Goellner JR. Gastric leiomyosarcoma: Prognostic factors and surgical management. Arch Surg 1991; 126: 985–990.GrantCS]]KimCH]]FarrugiaG]]ZinsmeisterA]]GoellnerJRGastric leiomyosarcoma: Prognostic factors and surgical managementArch Surg1991126985 12. Lee JS, Nascimento AG, Farnell MB, Carney JA, Harmsen WS, Ilstrup DM. Epithelioid gastric stromal tumors (leiomyoblastomas): A study of fifty-five cases. Surgery 1995; 118: 653–661.LeeJS]]NascimentoAG]]FarnellMB]]CarneyJA]]HarmsenWS]]IlstrupDMEpithelioid gastric stromal tumors (leiomyoblastomas): A study of fifty-five casesSurgery1995118653 13. Persson S, Kindblom LG, Angervall L, Tisell LE. Metastasizing gastric epithelioid leiomyosarcomas (leiomyoblastomas) in young individuals with long-term survival. Cancer 1992; 70: 721–732.PerssonS]]KindblomLG]]AngervallL]]TisellLEMetastasizing gastric epithelioid leiomyosarcomas (leiomyoblastomas) in young individuals with long-term survivalCancer199270721 14. Ballarini C, Intra M, Ceretti AP, Prestipino F, Bianchi FM, Sparacio F, et al. Gastrointestinal stromal tumors: A “benign” tumor with hepatic metastasis after 11 years. Tumori 1998; 84: 78–81.BallariniC]]IntraM]]CerettiAP]]PrestipinoF]]BianchiFM]]SparacioFGastrointestinal stromal tumors: A “benign” tumor with hepatic metastasis after 11 yearsTumori19988478 15. Rosai J. Gastrointestinal tract: Stromal tumors, in Rosai J (ed): Ackerman's Surgical Pathology. St. Louis, Mosby, 1996, ed 8, pp 645–648. 16. Appelman HD, Lewin KJ. Mesenchymal tumors and tumor-like proliferations, in Lewin KJ, Appelman HD: Atlas of Tumor Pathology: Tumors of the Esophagus and Stomach. Washington, DC, Armed Forces Institute of Pathology, 1997, vol 18, 3rd series, pp 405–456.
