Abstract | March 11, 2024

Association between Red Cell Distribution Width (RDW), Maximal Oxygen Consumption (VO2 max) and Delta Heart Rate in Postural Orthostatic Tachycardia Syndrome (POTS) or Postural Symptoms Without Tachycardia (PSWT) patients

Jawad Shahid, MBBS, Cardiology, Extern, The Heartbeat Clinic, McKinney, Tx

Smriti Awasthi, Cardiology, Student extern, The Heartbeat Clinic, McKinney, Tx; kazma Kulsoom, MPH, Cardiology, Biostatistician, The Heartbeat Clinic, McKinney, Tx; Amna Butt, MBBS, Cardiology, Extern, The Heartbeat Clinic, McKinney, Tx; and Amer Suleman, MD, Cardiology, Physician, The Heartbeat Clinic, McKinney, Tx.

Learning Objectives

  1. To explore the association between RDW, VO2 max, and Delta HR in individuals with POTS or PSWT, to identify any significant hematological and cardiovascular differences

Background: Postural Orthostatic Tachycardia Syndrome (POTS) is an autonomic disorder which is characterized by an abnormal increase in Heart Rate of more than 30 beats per minute upon standing. Postural symptoms without tachycardia (PSWT) is a condition which mimics the same symptoms as POTS without significant increase in Heart Rate. Red Cell Distribution Width (RDW) is a measurement of variability in red cell size which has been indicative of prognosis in various cardiovascular diseases. VO2 max is an ability of the person to utilize maximal oxygen during exercise. This study aims to explore the relationships between RDW, VO2 max, and Delta HR to enhance the prognostic value in clinical setting in POTS or PSWT patients.

Methods: A comparative study design was used in this research. A random data of 158 individuals with POTS or PSWT were selected from The Heartbeat Clinic, Texas. RDW, VO2 max and Delta HR were recorded through blood reports and metabolic stress test reports. For arranging and analyzing the data, SPSS 29.0 was used.

Results: Out of 158 POTS or PSWT patients 145(91.8%) were females whereas 13(8.2%) were males. For this comparative analysis, One-way ANOVA test was applied on variables. The obtained significance value upon the association between RDW with VO2 max and Delta HR was 0.087 and 0.179 respectively. The significance values were higher than 0.05 which showed that there was no association between RDW, VO2 max and Delta HR in POTS or PSWT patients.

Conclusion: It is concluded that RDW has no significant association with VO2 max and Delta HR. Elevated RDW has no bad prognosis on VO2 max and Delta HR in POTS or PSWT patients.

References and Resources

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