Introduction:
Hypergranulation tissue is an excessive growth of granulation tissue in a wound and is a problem that can be encountered in burn care when wounds take a significant time to heal including at burn sites themselves or even at skin graft donor sites. Many different wound care regimens have been devised to address this problem; however, often, these methods are painful or expensive and can lead to worsening of the hypergranulation tissue due to local inflammation and irritation or treating the underlying problems with hypergranulation tissue. We have devised a new topical treatment for hypergranulation tissue that has significantly decreased our time of treating the hypergranulation tissue as well as the time until healing of the wound or donor site.

Methods:
We have initiated a protocol of once hypergranulation tissue is identified, we start once a day topical application of a mixture of polysporin (containing bacitracin and polymyxin b) and 0.1% triamcinolone cream. These two products are mixed into a slurry and applied over the area of hypergranulation tissue and then dressed with a nonstick gauze dressing.

Results:
By utilizing this novel topical mixture, we have been able to see improvement and lessening of our areas of hypergranulation tissue within 48-72 hours from initial application and have noted improvement in the extent of these wounds.

Conclusions:
Hypergranulation tissue is an often-encountered part of wound care and wound healing. Many different interventions have been devised to lessen the burden of the hypergranulation tissue; however, these other methods can have several side effects and minimal improvement. We present a novel combination of a daily topical application of polysporin mixed with 0.1% triamcinolone cream. This method has led to improvement in the hypergranulation tissue and eventual complete resolution of the hypergranulation tissue.