Invited Commentary

Commentary on “A Dose-Response Analysis of Crystalloid Administration during Esophageal Resection”

Authors: Kyle J. Kalkwarf, MD

Abstract

In this issue of the Southern Medical Journal, Smith and Nossaman retrospectively examined patient records for 100 consecutive esophageal surgeries to assess intraoperative intravenous fluid with outcomes.1 They found a dose-response relation associating intraoperative crystalloid administration with decreased length of stay and adverse events.
Posted in: Gastroenterology56

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References

1. Smith M, Nossaman B. A dose-response analysis of crystalloid administration during esophageal resection. South Med J 2019;112:412-418.
2. Shoemaker WC, Appel PL, Kram HB, et al. Prospective trial of supranormal values of survivors as therapeutic goals in high-risk surgical patients. Chest 1988;94:1176-1186.
3. Gattinoni L, Brazzi L, Pelosi P, et al. A trial of goal-oriented hemodynamic therapy in critically ill patients. SvO2 Collaborative Group. N Engl J Med 1995;333:1025-1032.
4. Brandstrup B, Tønnesen H, Beier-Holgersen R, et al. Effects of intravenous fluid restriction on postoperative complications: comparison of two perioperative fluid regimens: a randomized assessor-blinded multicenter trial. Ann Surg 2003;238:641-648.
5. Cotton BA, Guy JS, Morris JA, Jr et al. The cellular, metabolic, and systemic consequences of aggressive fluid resuscitation strategies. Shock 2006;26:115-121.