SMJ Article | Original Article

Risk of Nephrolithiasis in Cirrhosis: A Comparison between MASLD Cirrhosis and Cirrhosis Due to Other Etiologies

Objectives: Nephrolithiasis is a systemic condition influenced by metabolic disorders, with rising prevalence worldwide. Although several studies have investigated the relationship between metabolic-associated steatotic liver disease (MASLD) and nephrolithiasis, few have focused on cirrhosis-specific etiologies. As the epidemiology of cirrhosis shifts from viral and alcohol-related causes to metabolic dysfunction-related etiologies,...

Posted in: Liver Disease10

SMJ Article | Perspectives

Know Your Guidelines: American Journal of Gastroenterology Clinical Guidelines on Acute Liver Failure

Acute liver failure (ALF) is defined as acute liver injury complicated by encephalopathy and coagulopathy in patients without previous cirrhosis. The most common causes of acute liver injury are acetaminophen hepatotoxicity, drug reactions, and hepatitis B infection. The signs and symptoms of ALF include jaundice, abdominal pain, edema, malaise, confusion,...

Posted in: Gastroenterology46

SMJ Article | Review Article

Liver Fibrosis and Cardiovascular Events

Objectives: Liver fibrosis represents a common sequela of nonalcoholic fatty liver disease (NAFLD) and other chronic liver diseases. Noninvasive liver fibrosis scores (LFSs) aim to evaluate the severity of liver fibrosis. Whether LFSs can predict the risk of future cardiovascular events (CVEs) remains unclear. This systematic review aimed to clarify...

Posted in: Liver Disease10

SMJ Article | Original Article

A Cohort Study of Lt. Col. Luke J. Weathers VA Medical Center Patients with Positive FIT and Incomplete GI Evaluation during the COVID-19 Pandemic

Objectives: The reasons for and incidence of delay in screening colonoscopies during the coronavirus disease 2019 (COVID-19) pandemic are of major public health interest. The risks and reasons for delay likely vary between public and private institutions. This research sought to analyze data regarding the completion of screening colonoscopies after...

Posted in: Gastroenterology46

SMJ Article | Original Article

Efficacy and Safety of Direct Oral Anticoagulants Compared to Warfarin in Patients with Cirrhosis and Splanchnic Vein Thrombosis

Objective: The incidence of splanchnic vein thrombosis (SVT) is reported to be

Posted in: Liver Disease10

SMJ Article | Original Article

Surging Liver Transplantation for Nonalcoholic Steatohepatitis from 2000–2022: A National Database Study

Objectives: Our aim was to provide an up-to-date, large-scale overview of the trends and clinicodemographics for NASH LTs performed in the United States compared with all other LT indications between 2000 and 2022. We also examined the demographic factors that will predict future demand for NASH LT. Methods: Our analysis...

Posted in: Liver Disease10

SMJ Article | Review Article

The Epidemiology and Clinical Presentation of Pancreatic Divisum: A Case Series of 57 Case Reports

Objectives: Pancreatic divisum (PD) is the second most common congenital abnormality of the pancreatic duct, which affects 2% to 3% of the population. Most of the population remains asymptomatic, but in people who present with symptoms, it can be a cause of anguish and should be recognized. The main goal...

Posted in: Gastroenterology46

SMJ Article | Original Article

Effects of the COVID-19 Pandemic on Colectomy Outcomes for Inflammatory Bowel Disease

Objectives: Inflammatory bowel disease (IBD) encompasses Crohn’s disease (CD) and ulcerative colitis (UC). These two chronic inflammatory conditions can differ in severity, presentation, and anatomical localization, and can greatly affect quality of life if not managed properly. Given the many healthcare challenges during the coronavirus disease 2019 pandemic, we studied...

Posted in: Gastroenterology46

SMJ Article | Original Article

Biennial Endoscopic Surveillance of Gastrointestinal Metaplasia and Its Subtypes Reduces Gastric Cancer Mortality and Is Cost-Effective in a Markov State Transition Model

Objectives: Gastric cancer in the United States has a low survival rate mainly because of the late stage of diagnosis. Furthermore, there are no well-established guidelines concerning screening and surveillance even for higher risk patients such as those with nondysplastic noncardia gastrointestinal metaplasia (GIM), and thus they are not routinely...

Posted in: Gastroenterology46

SMJ Article | Original Article

Racial Disparities in Clinical Outcomes of Emergency Colectomies for Diverticulitis

Objectives: The literature suggests that there are ongoing racial disparities in healthcare outcomes between patients in White and non-White populations. As such, we examined the outcomes of patients who underwent an emergency colectomy for diverticulitis. Methods: We identified 4841 White and 590 non-White patients, which include Black/African American and Asian...

Posted in: Gastroenterology46

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