SMJ Article | Perspectives

Know Your Guidelines Series: Diagnosis and Management of Nonalcoholic Fatty Liver Disease in Primary Care and Endocrinology Clinical Settings

Nonalcoholic fatty liver disease (NAFLD) represents a spectrum of liver disease without ongoing or significant alcohol use that ranges from hepatic steatosis to cirrhosis. NAFLD is associated with obesity, insulin resistance, type 2 diabetes mellitus (T2DM), hypertension, and dyslipidemia.1,2 Nonalcoholic steatohepatitis (NASH) represents the progression of NAFLD with at least...

Posted in: Endocrinology, Diabetes, and Metabolism15

SMJ Article | Original Article

Type 2 Diabetes Mellitus and Helicobacter pylori Eradication in a Clinical Population

Objectives: Eradication of Helicobacter pylori reduces the risk of gastric cancer (GC). Individuals with type 2 diabetes mellitus (T2DM) are known to be at increased risk for GC. In a cohort of H. pylori-positive individuals, we assessed whether those with T2DM were at risk of persistent infection following H. pylori...

Posted in: Endocrinology, Diabetes, and Metabolism15

SMJ Article | Review Article

A Comprehensive Review of COVID-19–Associated Endocrine Manifestations

Coronavirus disease 2019 (COVID-19) has played a significant part in systematic damage, affecting lives and leading to significant mortality. The endocrine system is one of the systems affected by this pandemic outbreak. The relationship between them has been identified in previous and ongoing research. The mechanism through which severe acute...

Posted in: Endocrinology, Diabetes, and Metabolism15 Infectious Disease121

SMJ Article | Original Article

Retrospective Analysis of Hospitalized Patients with Type 2 Diabetes Mellitus Treated with Glucagon-Like Peptide 1 Receptor Agonist Therapy

 Objectives: The use and overall benefit of glucagon-like peptide-1 (GLP-1) receptor agonist therapy for hospitalized patients with type 2 diabetes mellitus (DM) with chronic kidney disease (CKD) has limited data regarding impact and safety. We studied the impact and safety of GLP-1 receptor agonist therapy in hospitalized DM patients with...

Posted in: Endocrinology, Diabetes, and Metabolism15

SMJ Article | Original Article

CME Article: Reducing Infection Rates with Enhanced Preoperative Diabetes Mellitus Diagnosis and Optimization Processes

Objectives: Hyperglycemia and increased preoperative hemoglobin A1c (HbA1c) are associated with perioperative morbidity and death. For nonurgent operations, adequate glycemic control before surgery is recommended. Our surgical practice needed a process for preoperative diabetes mellitus (DM) diagnosis and glycemic optimization. Methods: Our review of the existing preoperative evaluation process found...

Posted in: Endocrinology, Diabetes, and Metabolism15

SMJ Article | Original Article

CME Article: Pregnancy-Associated Diabetes Mellitus and Stillbirths by Race and Ethnicity among Hospitalized Pregnant Women in the United States

Objectives: Racial disparities in preexisting diabetes mellitus (PDM) and gestational diabetes mellitus (GDM) remain largely unexplored. We examined national PDM and GDM prevalence trends by race/ethnicity and the association between these conditions and fetal death. Methods: This was a retrospective cross-sectional analysis of 69,539,875 pregnancy-related hospitalizations from 2002 to 2017...

Posted in: Endocrinology, Diabetes, and Metabolism15 Pregnancy26

SMJ Article | Original Article

CME Article: Vessel Sealant Devices in Thyroidectomies: An ACS-NSQIP Study

Objectives: Thyroidectomies involve meticulous dissection of a highly vascularized organ and complications may develop, such as hematoma, hypocalcemia, and even hypoparathyroidism. Because some of these complications may be fatal, we sought to identify the differences in postthyroidectomy outcomes when the use of a vessel sealant device (VSD) such, as LigaSure...

Posted in: Endocrinology, Diabetes, and Metabolism15

SMJ Article | Original Article

Propensity Score Matching to Determine the Impact of Metformin on All-Cause Mortality in Older Veterans with Diabetes Mellitus

Objectives: To determine whether metformin is associated with reduced all-cause mortality in older adults with diabetes mellitus as compared with insulin or sulfonylureas, and to evaluate whether the metformin cumulative exposure followed a dose-response relation. Methods: Retrospective cohort study with propensity score matching inveterans 65 years old and older with...

Posted in: Endocrinology, Diabetes, and Metabolism15

SMJ Article | Original Article

CME Article: Risk of Silent Myocardial Infarction in Prediabetic Patients: A Case-Control Study in a Veteran Population

Objectives: In the management of cardiovascular disease, it is important to identify patients at risk early on, to provide interventions to prevent the disease and its complications. The goal of our study was to investigate the association between glucose levels and silent myocardial infarction (SMI) among patients, who consisted of...

Posted in: Cardiovascular Disease23 Endocrinology, Diabetes, and Metabolism15

SMJ Article | Original Article

Racial/Ethnic Disparities in the Incidence of Epithelial Ovarian Cancer in Florida by Histology, 2001–2015: Analysis of Trends

Objectives: Because the population in Florida is 25.6% Hispanic, it is possible to evaluate the influence of race and ethnicity within clinically relevant subgroups of women with epithelial ovarian cancer (EOC), including histology and tumor grade. This study explores racial/ethnic disparities in the incidence of EOC in Florida by histology...

Posted in: Ovarian Disorders And Female Reproductive Health2 Ovarian Disorders2

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