Pulmonary Disease

SMJ Article | Original Article

Annual FEV1 Loss in Patients with Noncystic Fibrosis Bronchiectasis and Affecting Factors

Objectives: Bronchiectasis is a chronic respiratory disease characterized by sputum production, cough, and several bronchial infections. Lung function is an important parameter to evaluate and study in patients with bronchiectasis. This study aimed to evaluate the annual changes in forced expiratory volume in one second (FEV1) and related factors in...

Posted in: Pulmonary Disease12

SMJ Article | Errata

Clinical Outcomes of Noninvasive Ventilation in Asthma, Bronchiectasis, and Other COPD: Erratum

In the February 2021 issue of Southern Medical Journal, in the article by Nemeh et al, “Clinical Outcomes of Noninvasive Ventilation in Asthma, Bronchiectasis, and Other COPD”, the third author’s last name was misspelled. The author’s name should have appeared as Emmanuella Oduguwa.

Posted in: Pulmonary Disease12

SMJ Article | Review Article

OPEN: An Epidemic Supplanted by a Pandemic: Vaping-Related Illness and COVID-19

Before the coronavirus disease 2019 (COVID-19) pandemic, vaping-related illness was the prevailing public health concern. The incidence of vaping-related illnesses—mainly e-cigarette, or vaping, product use–associated lung injury (EVALI)—went from a peak in September 2019 to a low in February 2020, and the Centers for Disease Control and Prevention decided to...

Posted in: Infectious Disease79 Pulmonary Disease12

SMJ Article | Original Article

CME Article: Clinical Outcomes of Noninvasive Ventilation in Asthma, Bronchiectasis, and Other COPD

Objectives: Chronic obstructive pulmonary disease (COPD) is a leading cause of mortality and disability worldwide. Use of noninvasive ventilation (NIV) appears to be associated with a significant decrease in frequency of exacerbation, hospital admissions, and mortality in patients with COPD. In this study, we sought to determine clinical outcomes, prevalence,...

Posted in: Pulmonary Disease12

SMJ Article | Perspectives

Oxygen Supplementation in COPD Exacerbation with Hypoxia and Hypercapnia: What Does the Evidence Show?

Chronic obstructive pulmonary disease (COPD) is projected to be the third leading cause of mortality worldwide in 2020, with an annual healthcare expenditure of $50 billion in the United States alone.1,2 Acute exacerbation of COPD (AECOPD), characterized by worsening cough, sputum production, and breathlessness (beyond day-to-day variation), is frequently associated...

Posted in: Infectious Disease79 Pulmonary Disease12

SMJ Article | Original Article

Association between Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers and Lung Cancer

Objectives: Angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) are the most commonly prescribed antihypertensives, with prior studies identifying a possible association between long-term use and increased rates of lung cancer. This study evaluated this potential association in a large population using propensity matching. Methods: This was a population-based...

Posted in: Lung Cancer1

SMJ Article | Original Article

Outcomes of Idiopathic Pulmonary Fibrosis Improve with Obesity: A Rural Appalachian Experience

Objectives: Obesity can be an independent predictor of fibrosis in tissues, including the liver, heart, and skin. We evaluated a rural Appalachian cohort of idiopathic pulmonary fibrosis (IPF) for its relation to obesity. Methods: Using American Thoracic Society 2018 diagnostic guidelines, an IPF cohort was systematically identified at an Appalachian...

Posted in: Pulmonary Disease12

Abstract | November 13, 2020

Brainstem Encephalitis as the Presenting Symptom of Pulmonary Large cell Neuroendocrine Carcinoma

Paraneoplastic Neurologic Syndromes (PNS) are remote effects of malignancy involving the nervous system not related to tumor invasion, compression, or metastasis. These syndromes are rare, with approximately 1% of adults with cancer having an associated PNS. They are immunologic in origin where malignancy triggers production of autoantibodies against various antigens of the nervous system, as antigens located on the tumor mimic those of the nervous system.

Posted in: Medical Oncology17 Neurology1 Pulmonary Disease6

Abstract | November 6, 2020

Solitary Pulmonary Nodule – An Unusual Presentation

In this abstract, we will be presenting a case of a unique pathological finding in a patient diagnosed with a solitary pulmonary nodule.

Posted in: Pulmonary Disease6

Abstract | November 6, 2020

A Rare Case of Tuberculosis Presenting as Vocal Cord Nodule, Submental Abscess and Tracheoesophageal Fistula in a Renal Transplant Recipient

Among transplant recipients, atypical bacterial infections are not uncommon. Tuberculosis (TB) can have unusual manifestations, especially in immunocompromised hosts. Diagnosis of TB should be considered if a patient born in TB-endemic area presents with unusual symptoms.

Posted in: Endocrinology, Diabetes, and Metabolism12 Infectious Disease9 Pulmonary Disease6

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