Infectious Disease

SMJ Article | Original Article

Safety Profile of Using Tocilizumab in the Treatment of Severely Ill Patients with COVID-19

Objectives: Tocilizumab, originally used in the treatment of autoimmune disorders such as rheumatoid arthritis, had its use expanded to treat hyperinflammatory changes in coronavirus disease 2019. The objective of this study was to evaluate the risk of secondary infections and gastrointestinal side effects in patients treated with tocilizumab for severe...

Posted in: Infectious Disease140

SMJ Article | Original Article

COVID-19 Patients with Kidney Disease and Completion of Remdesivir Treatment

Objectives: Remdesivir is a nucleotide analog used to treat coronavirus disease 2019 (COVID-19). We determined whether reduced kidney function is associated with the completion of a full course of remdesivir in hospitalized patients with COVID-19. Methods: This was a retrospective study of 1103 adults hospitalized with COVID-19. The primary outcome...

Posted in: Infectious Disease140

SMJ Article | Original Article

The Artist versus the Machine: Evaluating ChatGPT Efficacy in Antimicrobial Management for Pediatric Traumatic Wounds

Objectives: To evaluate the efficacy of Chat Generative Pre-Trained Transformer (ChatGPT) in generating antimicrobial management recommendations for pediatric patients with contaminated traumatic wounds, particularly in the absence of infectious disease (ID) consultation. Methods: Three pediatric cases involving severely contaminated traumatic injuries were retrospectively presented to ChatGPT-4, including clinical data such...

Posted in: Infectious Disease140

SMJ Article | Original Article

Preexposure Prophylaxis Provided in the Emergency Department: Clinician Perspectives

Objectives: The southern United States is facing a burden of human immunodeficiency virus (HIV) diagnoses, with 52% of new diagnoses made in the region. The emergency department (ED) is an important access point for patient care, especially given nationwide shortages in primary care appointments. The objective of our study was...

Posted in: Infectious Disease140 Acquired Immunodeficiency Syndrome (AIDS) And Human Immunodeficiency Virus (HIV) Infection22

SMJ Article | Original Article

Outbreak Investigation of Mycobacterium abscessus Infections

Objective: Nontuberculous mycobacteria are ubiquitous in the environment and difficult to eliminate from contaminated water sources. The prevalence of Mycobacterium abscessus is particularly high in the southeastern United States. M. abscessus infections have become a particularly concerning source of outbreaks in healthcare settings, and can lead to substantial patient morbidity...

Posted in: Infectious Disease140

SMJ Article | Original Article

Preexposure Prophylaxis to Prevent HIV Acquisition: Perceptions among Sexual and Gender Minority Individuals in North Carolina

Objectives: Sexual and gender minority (SGM) communities at increased risk of human immunodeficiency virus (HIV) may be underprescribed preexposure prophylaxis (PrEP), but PrEP research on SGM communities other than transgender women and cisgender men who have sex with men is limited. We sought to better understand SGM individuals’ vulnerability to...

Posted in: Infectious Disease140 Acquired Immunodeficiency Syndrome (AIDS) And Human Immunodeficiency Virus (HIV) Infection22

SMJ Article | Original Article

Safety and Cost-Effectiveness of Hospital at Home in Patients with COVID-19

Objectives: The coronavirus disease 2019 (COVID-19) pandemic significantly affected the capacity of health systems across the United States. Although not widely used before the pandemic, the hospital-at-home (HaH) model emerged as a potential strategy to alleviate hospital burden by providing hospital-level care in the home setting. This study aims to...

Posted in: Infectious Disease140

SMJ Article | Original Article

Factors Affecting Gastroenterologists’ Fear When Performing Endoscopies during the COVID Pandemic: Results of a US National Survey

Objectives: The coronavirus disease 2019 (COVID-19) pandemic affected the practice of gastroenterology. Endoscopic procedures are aerosolizing procedures that carry the risk of COVID-19 transmission. Our national survey examined factors affecting gastroenterologists’ fear of contracting COVID-19 during endoscopy. Methods: An institutional review board–approved multicenter cross-sectional study used a snowball sample approach...

Posted in: Infectious Disease140

SMJ Article | Original Article

Effect of COVID-19 on Emergency Department Visits for Suicidal Ideation and Suicide Attempts among South Carolina Youth

Objectives: Evidence suggests that the coronavirus disease 2019 pandemic negatively affected children’s mental health (MH). The emergency department (ED) is often the first point of contact with a physician for youth who are experiencing suicidal thoughts and behaviors. Population-level reports of ED utilization in South Carolina for suicidal ideation (SI)...

Posted in: Infectious Disease140

SMJ Article | Original Article

Examining Provider Attitudes and Barriers toward Prescribing PrEP within Primary Care Settings in Alabama

Objectives: Human immunodeficiency virus (HIV) preexposure prophylaxis (PrEP) is an effective HIV prevention tool. Expanding PrEP access and utilization is made possible by incorporating it into primary care practice. This study explored the barriers in and attitudes toward prescribing PrEP to adults among primary care providers (PCPs) in Alabama, a...

Posted in: Infectious Disease140 Acquired Immunodeficiency Syndrome (AIDS) And Human Immunodeficiency Virus (HIV) Infection22

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