Rapid Response

To Dig or Not to Dig: A Lethal Question in Atrial Fibrillation?

Authors: Juan Tamargo MD, PhD, FESC, José López-Sendón MD, PhD, FESC

Abstract

Despite digoxin being considered a class I indication for rate control in many patients with persistent and permanent atrial fibrillation, with or without heart failure, its long-term efficacy and safety remains uncertain. Well-designed, multicenter, randomized clinical trials are necessary to clarify the safety profile of a drug daily used in thousands of patients.

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