Review Article

α1-Antitrypsin Deficiency and Liver Cirrhosis in Adults

Authors: MICHAEL P. SASSARIS MD, WILHELM TRINKL MD, RAO MEKA MD, PAULINO GONZALES MD, ORLANDO TORRES MD, RICHARD LEACH MD, FRED M. HUNTER MD

Abstract

ABSTRACT: Although cirrhosis of the liver caused by α1-antitrypsin deficiency is not uncommon in children, only a few cases have been described in adults. We have seen three such patients—one man and two women, ranging in age from 57 to 66 years. These cases show the wide spectrum of this genetically influenced disease.

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References