SMJ Article | Review Article
The Moreton Lecture Series: The Renin-Angiotensin-Aldosterone System—Physiology, Pathophysiology, and Pharmacological Inhibition
The renin-angiotensin-aldosterone system (RAAS) is a complex regulator comprising hormones, proteins, and enzymes. The discovery of the RAAS and its pharmacological manipulation has been essential in the management of cardiovascular diseases, including hypertension. Beyond the benefits of hypertension, RAAS inhibition has implications for heart failure, atherosclerotic disease, and kidney disease....