SMJ Article | Review Article

The Moreton Lecture Series: The Renin-Angiotensin-Aldosterone System—Physiology, Pathophysiology, and Pharmacological Inhibition

The renin-angiotensin-aldosterone system (RAAS) is a complex regulator comprising hormones, proteins, and enzymes. The discovery of the RAAS and its pharmacological manipulation has been essential in the management of cardiovascular diseases, including hypertension. Beyond the benefits of hypertension, RAAS inhibition has implications for heart failure, atherosclerotic disease, and kidney disease....

Posted in: Hypertension10

SMJ Article | Original Article

Management of Pulmonary Embolism: A Single-Center Experience

Objective: Pulmonary embolism (PE) is the third leading cause of cardiovascular death. The objective of this study was to examine the current management of pulmonary embolism at a single academic institution. Methods: With institutional review board approval, we conducted a retrospective chart review of 805 encounters among 775 patients presenting...

Posted in: Cardiovascular Disease27

SMJ Article | Original Article

Improving Hypertension and Diabetes Mellitus Control with a Dedicated Patient Navigator

Objectives: Hypertension and diabetes mellitus (DM) are the leading causes of cardiovascular, cerebrovascular, and chronic kidney diseases. They affect an estimated 47% and 11% of Americans, respectively. In this study, we assessed whether a dedicated patient navigator embedded within a patient-centered medical home (PCMH) using a structured panel management and...

Posted in: Endocrinology, Diabetes, and Metabolism17 Hypertension10

SMJ Article | Original Article

A Curriculum on Advanced Topics in Hypertension for Internal Medicine Residents

Objectives: Hypertension (HTN) affects nearly half of US adults. Our multi-institutional survey revealed that Internal Medicine residents lack proficiency in advanced HTN topics. We developed a curriculum to address knowledge gaps in these topics and aimed to assess the effects of the curriculum on residents’ confidence, desire for future training,...

Posted in: Hypertension10

SMJ Article | Review Article

Elevated Lp(a): Guidance for Identifying and Managing Patients

Key Points Elevated lipoprotein(a) (Lp(a)) is considered an independent and causal risk factor for atherosclerotic cardiovascular disease (ASVCD) and calcific aortic valve disease, affecting approximately 20% of individuals. Lp(a) levels are established in youth and are almost exclusively genetic and minimally affected by nonpharmacologic interventions. Clinicians should suspect elevated Lp(a)...

Posted in: Cardiovascular Disease27

SMJ Article | Perspectives

White Coat Hypertension: A Benign Finding or a Masked Risk Factor?

A role of the primary care physician is to identify and manage patient risk factors. An easily identified risk factor is hypertension, especially considering its clear association with the development of various negative health outcomes. Studies have clearly demonstrated the benefits gained by the proper control of hypertension among patients,...

Posted in: Hypertension10

SMJ Article | Original Article

Availability of Specialty Services for Cardiovascular Prevention Practice in the Southeastern United States

Objectives: A comprehensive cardiovascular disease (CVD) prevention approach should address patients’ medical, behavioral, and psychological issues. The aim of this study was to understand the clinician-reported availability of a pertinent CVD preventive workforce across various specialties using a survey study in the southeastern United States, an area with a disproportionate...

Posted in: Cardiovascular Disease27 Miscellaneous Cardiovascular Disease (Physical Examination Findings, Murmurs)3

SMJ Article | Original Article

Heart Disease Knowledge and Awareness in African American and Hispanic Women

Objectives: Coronary heart disease (CHD) is the leading cause of morbidity and mortality among US women. Minority women have higher rates of CHD and are more likely to experience adverse outcomes. Because of racial disparities in CHD outcomes, the purpose of this study was to assess CHD knowledge and awareness...

Posted in: Cardiovascular Disease27

SMJ Article | Review Article

Comprehensive Review of Hypertensive Disorders Related to Pregnancy

Hypertensive disorder of pregnancy is a common complication during pregnancy that affects approximately 10% of pregnancies and is responsible for nearly 14% of maternal deaths worldwide. It affects the mother and the fetus simultaneously, sometimes putting the health of the mother and the fetus at odds with each other. It...

Posted in: Hypertension10 Pregnancy33

SMJ Article | Review Article

Direct Use of Clinical Tolerance Limits for Assessing the Degree of Agreement between Two Methods of Measuring Blood Pressure

A large number of new methods of measuring blood pressure (BP) have recently emerged with advances in technology. Different methods of measuring BP generally provide varying readings compared with one another. Clinicians must decide how to respond to these variations and how to assess the degree of agreement. Clinical agreement...

Posted in: Hypertension10

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