Abstract
Abstract:The coexistence of multiple and synchronous primary neoplasms in the genitourinary system has rarely been described in the literature. To our knowledge, this is the first report of a very rare tumor, a “tubulocystic carcinoma,” simultaneously occurring with micropapillary urothelial carcinoma in the bladder and clear cell type renal cell carcinoma in the same kidney. Tubulocystic carcinoma is a recently entitled tumor. It had been thought to arise from the distal collecting duct for a period of time and was therefore named as a low-grade collecting duct carcinoma. Microscopically, the tumor is defined as being tubulocystic or having tubulopapillary architecture and a low nuclear grade with hobnail morphology. Its progression and treatment protocol are uncertain.
This content is limited to qualifying members.
If you have an existing account please login now to access this article or view purchase options.
Create a free account, then purchase this article to download or access it online for 24 hours.
Create a free account, then purchase a subscription to get complete access to all articles for a full year.
References
References1. Azoulay S, Vieillefond A, Paraf F, et al. Tubulocystic carcinoma of the kidney: a new entity among renal tumors. Virchows Arch 2007;451:905–909.AzoulayS]]VieillefondA]]ParafF&etal;Tubulocystic carcinoma of the kidney: a new entity among renal tumors.Virchows Arch2007451905-9092. Pereira Arias JG, Ateca Díaz-Obregón R, Gutiérrez Díez JM, et al. [Synchronous association of Bellini collecting ducts and pyelic transitional cell carcinoma]. Actas Urol Esp 1997;21:990–996 [in Spanish].3. Charney DA, Tomasula JR. Low-grade collecting duct carcinoma of the kidney: a potential mimic of conventional clear cell carcinoma. Internet J Pathol 2001;2:1.CharneyDA]]TomasulaJRLow-grade collecting duct carcinoma of the kidney: a potential mimic of conventional clear cell carcinoma.Internet J Pathol2001214. Farah R, Ben-Izhak O, Munichor M, et al. Low-grade renal collecting duct carcinoma. A case report with histochemical, immunohistochemical, and ultrastructural study. Ann Diagn Pathol 2005;9:46–48.FarahR]]Ben-IzhakO]]MunichorM&etal;Low-grade renal collecting duct carcinoma. A case report with histochemical, immunohistochemical, and ultrastructural study.Ann Diagn Pathol2005946-485. MacLennan GT, Farrow GM, Bostwick DG. Low grade collecting duct carcinoma of the kidney: report of 13 cases of low-grade mucinous tubulocystic renal carcinoma of possible collecting duct origin. Urology 1997;50:679–684.MacLennanGT]]FarrowGM]]BostwickDGLow grade collecting duct carcinoma of the kidney: report of 13 cases of low-grade mucinous tubulocystic renal carcinoma of possible collecting duct origin.Urology199750679-6846. Eble JN, Sauter G, Ebstein JI, et al. World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Urinary System and Male Genital Organs. Lyon, France, IARCC, 2004.EbleJN]]SauterG]]EbsteinJI&etal;World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Urinary System and Male Genital Organs.Lyon, FranceIARCC20047. Skinnider BF, Folpe AL, Hennigar RA, et al. Distribution of cytokeratins and vimentin in adult renal neoplasms and normal renal tissue: potential utility of a cytokeratin antibody panel in the differential diagnosis of renal tumors. Am J Surg Pathol 2005;29:747–754.SkinniderBF]]FolpeAL]]HennigarRA&etal;Distribution of cytokeratins and vimentin in adult renal neoplasms and normal renal tissue: potential utility of a cytokeratin antibody panel in the differential diagnosis of renal tumors.Am J Surg Pathol200529747-7548. Pan CC, Chen PC, Ho DM. The diagnostic utility of MOC31, BerEP4, RCC marker and CD10 in the classification of renal cell carcinoma and renal oncocytoma: an immunohistochemical analysis of 328 cases. Histopathology 2004;45:452–459.PanCC]]ChenPC]]HoDMThe diagnostic utility of MOC31, BerEP4, RCC marker and CD10 in the classification of renal cell carcinoma and renal oncocytoma: an immunohistochemical analysis of 328 cases.Histopathology200445452-4599. Kafé H, Verbavatz JM, Cochand-Priollet B, et al. Collecting duct carcinoma: an entitiy to be redefined? Virchows Arch 2004;445:637–640.KaféH]]VerbavatzJM]]Cochand-PriolletB&etal;Collecting duct carcinoma: an entitiy to be redefined?Virchows Arch2004445637-64010. Amin MB, MacLennan GT, Paraf F, et al. Tubulocystic carcinoma of the kidney: clinicopathologic analysis of 29 cases of a distinctive rare subtype of renal cell carcinoma. Mod Pathol 2004;17:137A.AminMB]]MacLennanGT]]ParafF&etal;Tubulocystic carcinoma of the kidney: clinicopathologic analysis of 29 cases of a distinctive rare subtype of renal cell carcinoma.Mod Pathol200417137A11. MacLennan GT, Bostwick DG. Tubulocystic carcinoma, mucinous tubular and spindle cell carcinoma, and other recently described rare renal tumors. Clin Lab Med 2005;25:393–416.MacLennanGT]]BostwickDGTubulocystic carcinoma, mucinous tubular and spindle cell carcinoma, and other recently described rare renal tumors.Clin Lab Med200525393-41612. Radhakrishnan A, Maclennan GT, Hennigar RA, et al. Ultrastructural and immunohistochemical (IHC) appraisal of tubulocystic carcinoma (TCCa) of the kidney: histogenetic and diagnostic implications. Mod Pathol 2005;18:160A.RadhakrishnanA]]MaclennanGT]]HennigarRA&etal;Ultrastructural and immunohistochemical (IHC) appraisal of tubulocystic carcinoma (TCCa) of the kidney: histogenetic and diagnostic implications.Mod Pathol200518160A13. Amin MB, MacLennan GT, Gupta R, et al. Tubulocystic carcinoma of the kidney: clinicopathologic analysis of 31 cases of a distinctive rare subtype of renal cell carcinoma. Am J Surg Pathol 2009;33:384–392.AminMB]]MacLennanGT]]GuptaR&etal;Tubulocystic carcinoma of the kidney: clinicopathologic analysis of 31 cases of a distinctive rare subtype of renal cell carcinoma.Am J Surg Pathol200933384-39214. Yang XJ, Zhou M, Hes O, et al. Tubulocystic carcinoma of the kidney: clinicopathologic and molecular characterization. Am J Surg Pathol 2008;32:177–187.YangXJ]]ZhouM]]HesO&etal;Tubulocystic carcinoma of the kidney: clinicopathologic and molecular characterization.Am J Surg Pathol200832177-18715. Yousef GM, Ejeckam GC, Best LM, et al. Collecting duct carcinoma associated with oncocytoma. Int Braz J Urol 2005;31:465–467.YousefGM]]EjeckamGC]]BestLM&etal;Collecting duct carcinoma associated with oncocytoma.Int Braz J Urol200531465-467
