Case Report
A Massive Pulmonary Hemorrhage Resulting in Cavitation Occurring in a Case of Hemophilia A Associated with Diabetes Mellitus
Abstract
THE AVAILABILITY of concentrated antihemophilic factor (AHF) from human and animal sources has provided us with a more convenient treatment for bleeding in patients with hemophilia. However, the prevention of bleeding is still a difficult problem in extending the life of hemophiliacs; it has been reported that bleeding after injury and intracerebral bleeding in hemophilia are the cardinal causes of death among hemophiliacs in Japan.1Among the various bleeding sites in hemophilia, the pulmonary parenchyma appears to escape from this fatal complication: massive bleeding into the lung has not been reported, except in a recent paper by Pursel and Sherman, 2 who describe a case of classic hemophilia requiring pulmonary resection for continued bleeding into the lung bullae.We recently have had an opportunity to observe a patient with hemophilia A associated with overt diabetes who experienced massive bleeding into the upper lobe of the right lung, resulting in cavitation, during his hospital course. Because of the paucity of reports on the coexistence of hemophilia and diabetes, and because of the rarity of pulmonary bleeding as a complication of hemophilia, we will describe the clinical course of this patient.This content is limited to qualifying members.
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