Case Report

Androgen-Producing, Atypically Proliferating Endometrioid Tumor Arising in Endometriosis

Authors: JOHN L. POWELL, MD, G. PATRICK CONNOR, MD, GREGORY S. HENDERSON, MD, PhD

Abstract

A case of androgen-secreting borderline endometrioid tumor arising in endometriosis of the rectovaginal septum is presented. It occurred 10 years after total abdominal hysterectomy and bilateral salpingo-oophorectomy for extensive endometriosis of the fallopian tubes and ovaries, adenomyosis, and leiomyomas of the uterus. We believe 7 years of unopposed continuous oral estrogen replacement therapy contributed to the malignant transformation of the endometriosis.

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