Case Report

Brucella Glomerulonephritis: Case Report and Review of the Literature

Authors: Ihsan Ustun, MD, Levent Ozcakar, MD, Nilufer Arda, MD, Murat Duranay, MD, Emel Bayrak, MD, Kadir Duman, MD, Murat Atabay, MD, Basak Engin Cakal, MD, Kadri Altundag, MD, Serdar Guler, MD


The authors present the case of a 17-year-old shepherd who was diagnosed with diffuse proliferative glomerulonephritis and diffuse tubulointerstitial nephritis during the course of Brucella infection. The pathogenesis and the mechanism of renal involvement in brucellosis is discussed in light of the pertinent literature.

Key Points

* Brucella is a zoonotic disease with a very wide spectrum of clinical findings.

* Osteoarticular, cutaneous, genitourinary, nervous, respiratory, and hematologic system involvements can be encountered during the course of the infection.

* The nephritis in brucellosis is usually classified as three types: acute interstitial nephritis or pyelonephritis, chronic involvement with granulomas and caseification necrosis, and the renal involvement in association with Brucella endocarditis.

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