Abstract

AbstractIn a clinical study, 30 patients with moderate-to-severe herpes zoster neuralgia were treated with chlorprothixene administered orally or both orally and intramuscularly. Eleven patients experienced relief from pain within 24 hours, and 27 of the 30 experienced relief from all pain within 72 hours. There was only one known failure, one known serious side effect, no known complications, and no known recurrences. The following dosage schedule was used: for severe neuralgia, 50 to 100 mg intramuscularly initially, then 50 mg tablets orally every six hours for seven to ten days; for moderate neuralgia, 50 mg tablets orally given every six hours for four to ten days. Based on our clinical experience, it was concluded that chlorprothixene can be used effectively as an analgesic agent in the management of herpes zoster neuralgia.