Case Report

Cobalamin Pseudodeficiency Due to a Transcobalamin I Deficiency

Authors: BOBBI B. ADCOCK MD, JERRY T. McKNIGHT MD

Abstract

&NA; Cobalamin (vitamin B12) deficiency warrants appropriate evaluation because cobalamin is necessary in certain biochemical functions. R‐binder deficiency, which causes low cobalamin levels, is a rare and benign pseudodeficiency. If not further evaluated by determining levels of methylmalonic acid and homocysteine, however, such a patient would be given unneeded treatment. We report a case in which a patient has an R‐binder deficiency, specifically transcobalamin I deficiency, with a low vitamin B12 level but no true vitamin B12 deficiency.

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References