Case Report

Cocaine Abuse Complicating Acute Painful Episodes in Sickle Cell Disease

Authors: Brian Boulmay MD, Richard Lottenberg MD

Abstract

Abstract:We report three sickle cell patients with recent cocaine abuse who presented with typical symptoms of vaso-occlusion rapidly progressing to major organ dysfunction. Our experience suggests cocaine abuse is a risk factor for major complications of a sickle cell painful episode. Enhanced clinical and laboratory surveillance for organ dysfunction is indicated if a history of cocaine abuse is elicited. Evidence of organ failure should lead to consideration of early aggressive interventions such as transfusion therapy.

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