Case Report

Diffuse Malignant Peritoneal Mesothelioma Presenting as Intestinal Obstruction

Authors: John Griniatsos MD, Stavros Sougioultzis MD, Nikoletta Dimitriou MD, Vassilia Vamvakopoulou MD, Paris Alexandrou MD, Vassiliki Kyriakou MD, Athanassios Tzioufas MD, Efstathios Papalambros MD, Michalis Tzivras MD

Abstract

Abstract:Diffuse malignant peritoneal mesothelioma (DMPM) represents 90% of all peritoneal forms of mesothelioma. It affects mainly patients 50–69 years old. In 50% of cases there is a history of asbestos exposure. The clinical presentation of the disease is not characteristic: nonspecific abdominal pain, weight loss, and abdominal distension are common. Ascites occurs in 90% of the patients. Bowel obstruction is a late manifestation. We present three patients with DMPM, without a history of asbestos exposure and without ascites, who presented with complete bowel obstruction. All patients underwent emergency operations, and palliative surgical procedures were performed. Each patient died within 3 to 6 months postoperatively.

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