Editorial Comment on Djaladat's "The Effect on Aminophylline of Renal Colic"

Authors: Edward D. Kim, MD


In this well-designed study, Djaladat et al1 compared intravenous (IV) aminophylline infusion to placebo for pain control in patients presenting to an emergency room with acute renal colic. Using a visual analog scale, they reported that pain intensity was effectively controlled in 64% of treated patients compared with 17% of patients receiving placebo. Side effects were mild and infrequently reported.

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1. Djaladat H, Tajik P, Fard S, et al. The effect of aminophylline on renal colic: a randomized double blind controlled trial. South Med J 2007;100:1081–1084.
2. Parsons JK, Hergan LA, Sakamoto K, Lakin C. Efficacy of alpha-blockers for the treatment of ureteral stones. J Urol 2007;177:983–987.
3. Larkin GL, Peacock 4th, WF Pearl SM, et al. Efficacy of ketorolac tromethamine versus meperidine in the ED treatment of acute renal colic. Am J Emerg Med 1999;17:6–10.