The Southern Medical Journal (SMJ) is the official, peer-reviewed journal of the Southern Medical Association. It has a multidisciplinary and inter-professional focus that covers a broad range of topics relevant to physicians and other healthcare specialists.

SMJ // Article

Case Report

Eosinophilic Pleural Effusion Associated With Valproic Acid Administration

Authors: JACK KAUFMAN MD, IRENE M. O'SHAUGHNESSY MD

Abstract

ABSTRACT: A case of eosinophilic pleural effusion with peripheral blood eosinophilia is presented. No cause of the pleural effusion was found, but on cessation of valproic acid therapy, both the pleural effusion and eosinophilia resolved. Valproic acid should be added to the list of drugs associated with pleural fluid eosinophilia.

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