Case Report
Fluconazole-Carbamazepine Interaction
Abstract
The patient we describe had elevated carbamazepine serum concentrations during concomitant fluconazole administration (400 mg/day), including serial concentrations both before and after antifungal therapy. Since fluconazole is a known inhibitor of the cytochrome P-450 enzyme system, this suggests an inhibition of carbamazepine metabolism.This content is limited to qualifying members.
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