The Southern Medical Journal (SMJ) is the official, peer-reviewed journal of the Southern Medical Association. It has a multidisciplinary and inter-professional focus that covers a broad range of topics relevant to physicians and other healthcare specialists.

SMJ // Article

Original Article

Glycohemoglobin Determinations in Pregnant Diabetic Patients

Authors: CHRISTOS G. HATJIS MD, ELEANOR L. CAPELESS MD, LEON I. MANN MD

Abstract

ABSTRACT: Glycohemoglobins (GH), minor variants of hemoglobin A, are elevated in patients with diabetes mellitus. We examined the clinical usefulness of GH levels in human pregnancy. There was no correlation between GH levels and gestational age or neonatal birth weight. Insulin-dependent diabetics had higher GH levels than did normal controls (≥33 weeks gestation). There was a significant correlation between fasting plasma glucose concentration and GH levels in insulin-dependent diabetics, especially when the former was determined six to 12 weeks before GH determination. Because of the wide scatter of data and the a posteriori relationship, however, we were unable to use this information at the clinical level.

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References