Abstract

ABSTRACT: &NA; We report a case of Guillain‐Barré syndrome and associated cytomegalovirus infection during pregnancy. A 15‐year‐old black adolescent had progressive ascending paralysis and vague sensory symptoms during week 10 of her first pregnancy. Diagnosis of Guillain‐Barré syndrome was confirmed by electrophysiologic findings consistent with acute demyelinating polyradiculoneuropathy. A mild elevation of anti‐GM, antibodies was also detected. The patient improved with plasmapheresis treatment; however, fetal death occurred 10 weeks later. Cytomegalovirus placentitis was confirmed histologically. Acute demyelinating polyneuropathy during pregnancy warrants consideration of a concomitant, primary maternal and fetal cytomegalovirus infection.