Human Ehrlichiosis: Clinical and Ecological Challenges

Authors: John J. Openshaw, MSc, David L. Swerdlow, MD


Cases of tick-borne zoonotic diseases such as Rocky Mountain Spotted Fever, Lyme disease, and the human ehrlichioses are on the rise in the United States.1,2 These emerging diseases are complex in their ecology, often perplexing in their clinical presentation, and challenging to diagnose. Lisa Prince et al3 in this month's Journal present a case of human monocytic ehrlichiosis (HME) and describe aspects of clinical diagnosis in the acute setting and laboratory diagnosis using serology and PCR.

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