Original Article

Invasive Aspergillosis Treated With Adjunctive Hyperbaric Oxygenation A Retrospective Clinical Series at a Single Institution

Authors: LISARDO GARCÍA-COVARRUBIAS MD, DIANA M. BARRATT MD, MPH, ROBERT BARTLETT MD, STEPHEN METZINGER MD, KEITH VAN METER MD

Abstract

Background.Invasive aspergillosis is the leading cause of early death in many transplant centers and has a major impact on the management of hematologic malignancies. The mortality rate with current therapy (amphotericin B and surgery) has remained unacceptably high. In vitro data along with a few case reports have suggested a potential benefit of hyperbaric oxygen (HBO).

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References