Original Article

Lymphoepithelioma-Like Carcinoma of the Uterine Cervix

Authors: ELIZABETH N. SKINNER, MD, IRA R. HOROWITZ, MD, BHAGIRATH MAJMUDAR, MD

Abstract

We describe two rare cervical tumors having morphologic features closely resembling those of the nasopharyngeal lymphoepithelioma. This entity has historically been classified as a subtype of squamous cell carcinoma, but after reviewing the literature and the two cases presented here, we propose that this tumor is a distinct carcinoma of the cervix that differs from squamous cell carcinoma in that it carries a more favorable prognosis, typically affects a younger population of women, is more prevalent in noncaucasian populations (especially those of Asian descent), and lacks a clearly defined association with infection due to human papilloma virus (HPV).

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References