The Southern Medical Journal (SMJ) is the official, peer-reviewed journal of the Southern Medical Association. It has a multidisciplinary and inter-professional focus that covers a broad range of topics relevant to physicians and other healthcare specialists.

SMJ // Article

Primary Article

Mezlocillin Prophylaxis Against Infection After Cesarean Section: A Comparison of Techniques

Authors: J PATRICK LAVERY MD, K C HUANG MD, WILLIAM L. KOONTZ MD, JONATHAN REINSTINE MD, CARRIE MARCELL RN, NEVA ROSENBERG RN

Abstract

ABSTRACT: We studied 212 patients undergoing emergency cesarean section at an urban hospital. Four techniques of antibiotic prophylaxis were used, including single-dose and triple-dose parenteral therapy, parenteral and lavage therapy, and lavage therapy alone. One agent, mezlocillin, was used for all patients. There was no significant difference in surgically related infectious morbidity among the groups. This antibiotic proved efficacious when related to historical controls, and was the most economical of the modalities of administration studied.

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