Letter to the Editor
More Adverse Neurological Consequences of Metformin-Induced Vitamin B12 Deficiency
Abstract
To the Editor: We read with interest the landmark first case report of metformin-induced vitamin B12 deficiency causing neuropathy in a 69-year-old man having used metformin for three years by Dr. David Bell.1The link between metformin and neuropathy is further supported by a prospective case-control study conducted in 122 diabetics; fifty-nine of which had been treated with metformin for more than six months.2 The metformin treated patients were found to have depressed serum vitamin B12 levels and more severe clinical and electrophysiological measures of peripheral neuropathy.This content is limited to qualifying members.
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