Abstract
Abstract:A case of neurobrucellosis complicated by optic, abducens and vestibulocochlear nerve palsies is reported. Brucella melitensis was isolated in the cerebrospinal fluid, and the patient was diagnosed with retrobulbar neuritis. Despite medical treatment, the patient developed optic atrophy. Multiple cranial nerve involvement should be kept in mind in patients presenting with blurred vision and double vision, especially in regions where brucellosis is endemic.
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References
References1. Young EJ. Brucella Species, in Mandell GL, Bennet JE, Dolin R (eds): Principles and Practice of Infectious Diseases, Philadelphia, PA, Churchill Livingstone, 2005, ed 6, pp 2669–2674.2. Ministry of Health of Turkey. General Directorate of Primary Health Services. Available at: http://www.saglik.gov.tr. Accessed May 2, 2008.3. Yetkin MA, Bulut C, Erdinc FS, et al. Evaluation of the clinical presentations in neurobrucellosis. Int J Infect Dis 2006;10:446–452.YetkinMA]]BulutC]]ErdincFS&etal;Evaluation of the clinical presentations in neurobrucellosis.Int J Infect Dis200610446-4524. Karakurum Goksel B, Yerdelen D, Karatas M, et al. Abducens nerve palsy and optic neuritis as initial manifestation in brucellosis. Scand J Infect Dis 2006;38:8, 721–725.Karakurum GokselB]]YerdelenD]]KaratasM&etal;Abducens nerve palsy and optic neuritis as initial manifestation in brucellosis.Scand J Infect Dis2006388, 721-7255. Yilmaz M, Ozaras R, Mert A, et al. Abducent nerve palsy during treatment of brucellosis. Clin Neurol Neurosurg 2003;105:218–220.YilmazM]]OzarasR]]MertA&etal;Abducent nerve palsy during treatment of brucellosis.Clin Neurol Neurosurg2003105218-2206. Cagatay A, Karadeniz A, Ozsut H, et al. Hearing loss in patient with neurobrucellosis. South Med J 2006;99:1305–1306.CagatayA]]KaradenizA]]OzsutH&etal;Hearing loss in patient with neurobrucellosis.South Med J2006991305-13067. Vinod P, Singh MK, Garg RK, et al. Extensive meningoencephalitis, retrobulbar neuritis and pulmonary involvement in a patient of neurobrucellosis. Neurol India 2007;55:157–159.VinodP]]SinghMK]]GargRK&etal;Extensive meningoencephalitis, retrobulbar neuritis and pulmonary involvement in a patient of neurobrucellosis.Neurol India200755157-1598. Miyares FR, Deleu D, Elshafie SS, et al. Irreversible papillitis and ophthalmoparesis as a presenting manifestation of neurobrucellosis. Clin Neurol Neurosurg 2007;109:439–441.MiyaresFR]]DeleuD]]ElshafieSS&etal;Irreversible papillitis and ophthalmoparesis as a presenting manifestation of neurobrucellosis.Clin Neurol Neurosurg2007109439-4419. Haji-Abdolbagi M, Rasooli-Nejad M, Jafari S, et al. Clinical and laboratory finding in neurobrucellosis: review of 31 cases. Arch Iran Med 2008;11:21–25.Haji-AbdolbagiM]]Rasooli-NejadM]]JafariS&etal;Clinical and laboratory finding in neurobrucellosis: review of 31 cases.Arch Iran Med20081121-2510. McLean DR, Russel N, Khan MY. Neurobrucellosis: clinical and therapeutic features. Clin Infect Dis 1992;15:582–590.McLeanDR]]RusselN]]KhanMYNeurobrucellosis: clinical and therapeutic features.Clin Infect Dis199215582-59011. Pascual J, Combarros O, Polo JM, et al. Localized CNS brucellosis: report of 7 cases. Acta Neurol Scand 1988;78:282–289.PascualJ]]CombarrosO]]PoloJM&etal;Localized CNS brucellosis: report of 7 cases.Acta Neurol Scand198878282-28912. Valenza G, Kallmann B, Berend A, et al. Isolation of brucella melitensis from a patient with hearing loss. Eur J Clin Microbiol Infect Dis 2006;25:67–68.ValenzaG]]KallmannB]]BerendA&etal;Isolation of brucella melitensis from a patient with hearing loss.Eur J Clin Microbiol Infect Dis20062567-6813. Bodur H, Erbay A, Akinci E, et al. Neurobrucellosis in an endemic area of brucellosis. Scand J Infect Dis 2003;35:94–97.BodurH]]ErbayA]]AkinciE&etal;Neurobrucellosis in an endemic area of brucellosis.Scand J Infect Dis20033594-9714. Abd Elrazak M. Brucella optic neuritis. Arch Intern Med 1991;151:776–778.Abd ElrazakMBrucella optic neuritis.Arch Intern Med1991151776-77815. Romero M, Sánchez F, Fernández-Bolaños R, et al. [Optic neuritis as a clinical manifestation of neurobrucellosis]. Rev Neurol 1999;28:438 [in Spanish].16. Tunç M, Durukan H. Bilateral severe visual loss in brucellosis. Ocul Immunol Inflamm 2004;12:223–226.TunçM]]DurukanHBilateral severe visual loss in brucellosis.Ocul Immunol Inflamm200412223-226