Case Report
Propranolol-Related Bronchospasm in Patients Without History of Asthma
Abstract
PROPRANOLOL HYDROCHLORIDE is a beta-adrenergic antagonist used for the treatment of a variety of clinical disorders, including hypertension.1 Patients with a history of bronchospasm should not be given propranolol, since beta-antagonists may potentiate bronchospasm.2 However, there have been no case reports of propranolol-induced bronchospasm in the absence of a previous history of allergic problems such as asthma or hay fever. One patient without a prior history of asthma or other allergic reaction did develop acute laryngospasm while receiving propranolol,3 but the additive tartrazine was believed to be the offending agent. During the past four years we have observed three patients without a past allergic history who developed severe acute bronchospasm while taking propranolol. Hospitalization was required in all three cases. This report details the clinical courses of these patients.This content is limited to qualifying members.
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