Editorial

Respiratory CSI: Diagnosing Occupationally Related Lung Disease

Authors: Maureen R. Horton, MD

Abstract

In this issue of the Southern Medical Journal, Modi et al1 describe how working in a popcorn factory led to a devastating, irreversible lung disease: bronchiolitis obliterans.


Environmental and occupational insults causing respiratory disorders are often difficult to diagnose, because recognition requires a certain amount of detective work by the physician. Although a thorough environmental and occupational exposure is part of a complete patient history, it is often lost in today’s fast-paced medical visits. However, because the consequences of these potentially deadly exposures may not be obvious for years or even decades after the exposure, early detection and removal of the offending agent can be potentially life saving. Occupationally related injuries and illnesses have been estimated to affect upwards of 4.3 to 13.3 million Americans annually, with 5,800 to 63,000 job-related deaths and 862,200 work-related illness in 2004.2,3 Unfortunately, the presentation of these work-related illnesses is often protean, mimicking or exacerbating common illnesses such as asthma. Furthermore, the disorder may develop slowly with no acute illness, and the patient may be unaware of the developing disease until it is too late. Thus, the only “clue” to a job-related etiology for a current acute illness, exacerbation of a preexisting illness, or risk for a future disease is the occupational and environmental exposure history.

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References

1. Modi P, Yadava V, Sreedhar R, et al. A case of flavor-induced lung disease. South Med J 2008;101:541–542.
 
2. Leigh JP, Markowitz SB, Fahs M, et al. Occupational injury and illness in the United States. Estimates of costs, morbidity, and mortality. Arch Intern Med 1997;157:1557–1568.
 
3. Statistics BoL. Workplace Injuries and Illness in 2004. Washington, DC, US Department of Labor, 2005.
 
4. Parmet AJ, Von Essen S. Rapidly progressive, fixed airway obstructive disease in popcorn workers: a new occupational pulmonary illness? J Occup Environ Med 2002;44:216–218.
 
5. Centers for Disease Control and Prevention. Fixed obstructive lung disease in workers at a microwave popcorn factory—Missouri, 2000–2002. MMWR Morb Mortal Wkly Rep 2002;51:345–347.