The Southern Medical Journal (SMJ) is the official, peer-reviewed journal of the Southern Medical Association. It has a multidisciplinary and inter-professional focus that covers a broad range of topics relevant to physicians and other healthcare specialists.
SMJ // Article
Primary Article
Sarcoidosis and ELISA for Borrelia burgdorferi
Abstract
ABSTRACT: Lyme disease can be confirmed by detection of IgM and IgG antibodies against the causative pathogen Borrelia burgdorferi. Enzyme-linked immunosorbent assay (ELISA) can be confirmatory within weeks of symptom onset. Sarcoidosis has not previously been reported as one of the disease processes associated with a false-positive ELISA for Lyme disease. In our study, Lyme ELISA was obtained in 25 patients with various degrees of activity of sarcoidosis. ELISA was positive for Lyme disease in only one of these patients. Sarcoidosis may not be one of the diseases that commonly results in a false-positive Lyme ELISA.This content is limited to qualifying members.
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