Case Report

Septic Shock From the Administration of a Bacterially Contaminated Platelet Transfusion

Authors: PHILIP E. NEFF MD, KATHERINE PATTERSON KELLY MN, RN, JOSEPH D. TOBIAS MD

Abstract

ABSTRACTWe report the case of a 6-year-old boy who began to have fever and hypotension during the administration of a platelet transfusion. Subsequent investigation revealed the etiology to be bacterial contamination of the platelet product. Serratia marcescens was cultured from both the patient's blood and the platelet product. When fever and/or cardiorespiratory problems develop during the administration of blood products, possible bacterial contamination of the product must be considered so that appropriate therapy can be instituted. We discuss the etiology, possible preventive strategies, and the treatment of this problem.

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