Commentary

Treatment of Metastatic Renal Cell Carcinoma

Authors: KEITH HAGAN MD, J. DOUGLAS TRAPP MD, ROBERT K. RHAMY MD, VERNON H. REYNOLDS MD

Abstract

AbstractThe second known case of complete bony regression of metostatic renal cell carcinoma is presented. As in most cases reported, a tissue diagnosis of these lesions was lacking, but the roentgenographic picture clearly seemed to document the findings. At Vanderbilt, we favor an aggressive approach to this problem, mainly because of the unpredictability of the disease itself. Nephrectomy is always done when possible, and vinblastine sulfate (Velban) therapy, which has produced an objective response in approximately 30% of the patients in our series, certainly seems useful.

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References