Letter to the Editor
Virchow's Triad?
Abstract
Your journal recently published an interesting letter offering a unique perspective on the intent of Virchow's triad.1 Brotman et al successfully demonstrated that Rudolf Virchow postulated a triad as an explanation for the adverse consequences observed in the pulmonary vasculature following pulmonary embolism, and more specifically, as it pertained to the reaction elicited following experiments in which he introduced various foreign bodies into the venous circulation of dogs.2This content is limited to qualifying members.
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References
1. Brotman DJ, Deitcher SR, Lip GY, et al. Virchow's triad revisited. South Med J 2004;97:213–214.
2. Virchow RLK. Gesammelte Abhandlungen zur Wissenschaftlichen Medicin [Frankfurt, Meidinger Sohn & Co., 1856], in Virchow RLK: Thrombosis and Emboli (1846–1856). Matzdorff AC, Bell WR (transl). Canton, Science History Publications, 1998, pp 5–11, 110.
3. Owen CA. A History of Blood Coagulation. Rochester, Mayo Foundation for Medical Education and Research, 2001, pp. 169–180.
4. Dickson BC. Venous thrombosis: on the history of Virchow's triad. UTMJ 2004;81:166–171.
5. Wiseman R. Several Chirurgical Treatises. 2nd ed. London, Norton and Macock, 1686, pp. 64–66.
6. Owre A. Studies of the clinic and etiology of post-operative thrombosis. Acta Chir Scand 1929;65:1–111.
7. Hellsten WO. Phlebographic studies and heparin treatment. Acta Chir Scand 1942;87:1–296.
