Issue - Southern Medical Association

Original Article

CME Article: Body Mass Index and Self-Reported Compliance with General Health Care

Objectives: The relation between elevated body mass index (BMI)/overweight-obesity and compliance with health care remains unclear; some studies have demonstrated a relation whereas others have not. To add to the confusion, a number of studies have examined specialized populations (eg, patients with diabetes mellitus) and/or only one parameter of compliance…

Invited Commentary

Commentary on “Regional Variation in HIV Clinical Trials Participation in the United States”

During the last 2 decades, great strides have been made in the development of preventive and therapeutic interventions against human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS), including more effective antiretroviral regimens and the introduction of pre- and postexposure prophylaxis.1 Efforts to achieve a substantial and sustained decline in the incidence…

General Information

CME Instructions

Each CME activity should take approximately 1 hour to complete. Each CME activity includes the following: Full text article Article CME information CME test Evaluation Learner-directed phase CME activities within the online journal CME on the Southern Medical Association’s Web site can be accessed in the following ways: Through the online…

Review Article

Risk Assessment and Management of Anthracycline and HER2 Receptor Inhibitor-Induced Cardiomyopathy

With the advent and increased use of chemotherapeutic agents and radiation therapy, cancer survival rates have increased. With increased survival, both acute and chronic cardiotoxic adverse effects have emerged. The growing need for managing the treatment of individuals with chemotherapy-induced cardiotoxicity has led to the formation of cardio-oncology programs throughout…

Invited Commentary

Commentary on “Rules for Improving Pharmacotherapy in Older Adult Patients: Part 1 (Rules 1-5)”

It is not unusual for a clinician who is seeing an older patient for the first time to be confronted with a bagful of medications that the patient is taking. The busy clinician may wonder how he or she will be able to finish the visit in the allotted time….

Review Article

Rules for Improving Pharmacotherapy in Older Adult Patients: Part 1 (Rules 1-5)

The population of older adult patients in the United States is growing each year. Appropriate pharmacotherapy has allowed many older patients to live longer and maintain healthy lives. Unfortunately, the inappropriate utilization of medications can be harmful to older adult patients. Inappropriate pharmacotherapy may lead to overusing medications and polypharmacy….

Original Article

Epidemiology of Falls in Older Adults in Texas

Objectives: The expected increase in the US older adult population implies an increased risk of fall-related injury among these individuals. We describe the epidemiology of fall morbidity among older adults in Texas, a large US state with a diverse population base. Methods: Texas Behavioral Risk Factor Surveillance System 2010 data…

Review Article

Use of Sodium-Glucose Cotransporter Type 2 Inhibitors in Older Adults with Type 2 Diabetes Mellitus

Sodium-glucose cotransporter type 2 (SGLT2) inhibitors such as canagliflozin and dapagliflozin have been approved for the treatment of type 2 diabetes mellitus. A PubMed search was conducted of the literature from April 1996 to August 2014 to identify all human studies related to SGLT2 inhibitors. Pertinent guidelines of experts and…

Original Article

School-Based Adolescent Obesity Prevention Programming: Perceptions of School Personnel in Southern Appalachia

Objectives: Coordinated School Health (CSH) is a systematic approach to improving the health and well-being of school-age children. It is recommended for its potential to promote healthy weight in adolescents through strategic programming. Resources and programming for adolescent obesity prevention varies among schools, thereby limiting the intended benefits of CSH….

Letter to the Editor

Early Laparoscopic Cholecystectomy for Acute Cholecystitis: Is It Safe for Patients?

To the Editor: There is still controversy in the literature about the best timing for surgery in treating acute cholecystitis. Proponents of early laparoscopic cholecystectomy argue that this technique may reduce morbidity, conversion rates, mortality, and hospital costs.1 Others favor delayed surgery (>7 days) because there is a belief that…


CME Article: Teaching International Medicine to Medical Students: A Clinical Imperative

The 2014 Ebola virus epidemic, affecting multiple countries in west Africa, was the largest in history and the worst global public health emergency of our generation, with more than 10,000 cases and 5000 deaths at the time of this writing.1 Imported and locally acquired cases in the United States have…

Original Article

Effects of Cocaine-Positive Urine Screens on Serum Thyrotropin Levels in Patients Admitted to an Inpatient Mental Health Unit

Objective: To assess the effect of a positive urine screen for cocaine on thyrotropin (TSH, also thyroid-stimulating hormone) concentrations. Methods: In this retrospective cohort study, patients admitted to the mental health unit at an academic inpatient setting with a diagnosis of cocaine dependence or cocaine intoxication were routinely screened with…

Original Article

Regional Variation in HIV Clinical Trials Participation in the United States

Objectives: To ensure generalizability of clinical research results, it is important to enroll a heterogeneous population that is representative of the target clinical population. Earlier studies have found regional variation in participation in human immunodeficiency virus (HIV) clinical trials, with the lowest rates seen in the southern United States. Rates…

Review Article

Sodium-Glucose Cotransporter 2 Inhibitors: The New Option for Diabetes Mellitus Management

Type 2 diabetes mellitus continues to be a challenging disease to manage successfully. Beyond the first-line option metformin, there are a number of classes of medications from which to select. This article reviews the new sodium-glucose cotransporter 2 inhibitors canagliflozin and dapagliflozin, including their benefits, adverse effects, and potential place…

Letter to the Editor

Proposed Clinical and Endoscopic Predictors for Diagnosis of Gastrointestinal Kaposi Sarcoma

To the Editor: Gastrointestinal Kaposi sarcoma (KS) is often missed by superficial endoscopic biopsies because of its submucosal location. For example, among 30 patients undergoing gastrointestinal endoscopy with biopsy, the diagnosis was missed in 77% of biopsied lesions in a study published in 19851; among the first 26 patients undergoing…