Primary Article

Adenoacanthoma and Ulcerative Colitis Case Report and Review of the Literature



Squamous cell carcinoma and adenoacanthoma of the colon and rectum above the anal verge are uncommon lesions. A total of 48 cases have been reported since 1907: 23 squamous and 25 adenoacanthomas, including the present case. Five of these cases occurred in patients with ulcerative colitis: the present case, one of adenoacanthoma with predominantly keratinizing metastatic lesions and psammoma bodies, and 4 squamous cell carcinomas reported earlier. In addition, 4 of the remaining 43 cases occurred in patients with preceding or concomitant colon disease: one squamous cell lesion and one adenoacanthoma occurred in the cecum of 2 patients at the site of draining sinuses which had developed some years after appendectomies were performed; one squamous cell carcinoma occurred at the site of tuberculomas, and one at the site of schistosomiasis.

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