Case Report

Atopic Dermatitis, Eczema Herpeticum, Infectious Mononucleosis, and Depressed Cell‐Mediated Immunity

Authors: MAJ JAMES G. MARKS JR., MC, USAF

Abstract

An immunologic investigation was undertaken in a patient with atopic dermatitis and infectious mononucleosis complicated by eczema herpeticum. Humoral immunity was normal. The cell-mediated immune (CMI) response was temporarily depressed during the acute phase of the illness as measured by in vivo skin tests, and in vitro tests using T-lymphocyte population, macrophage inhibition factor, and lymphocyte transformation. It is postulated that the depression of CMI caused by infectious mononucleosis precipitated the development of eczema herpeticum in this patient.

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References