The Southern Medical Journal (SMJ) is the official, peer-reviewed journal of the Southern Medical Association. It has a multidisciplinary and inter-professional focus that covers a broad range of topics relevant to physicians and other healthcare specialists.

SMJ // Article

Perspectives

Balancing Relief and Risk: Managing Chronic Low Back Pain in Patients with Opioid Use Disorder

Authors: Vania Modesto-Lowe MD, MPH, Deanna Sgambato DMS, MHS, PA-C, Jasleen Kaur MD

Abstract

Chronic low back pain and opioid use disorder often occur together, creating clinical situations that are complex and emotionally charged. Low back pain remains a common cause of disability and a major contributor to opioid prescribing. Although guidelines recommend exercise and other non-opioid treatments as first-line care, patients with co-occurring opioid use disorder frequently have limited access to these services and are more likely to receive escalating opioid doses instead. Stigma, fragmented systems, and regulatory pressures further complicate care and strain clinical encounters. Integrated approaches that combine medication treatment for opioid use disorder with behavioral and rehabilitative pain strategies offer a more practical way to address both conditions at once. Emphasizing function, safety, and clear communication can help move care forward, even when broader structural barriers remain.

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References

1. Ferreira ML, de Luca K, Haile LM, et al. Global, regional, and national burden of low back pain, 1990-2020, its attributable risk factors, and projections to 2050: a systematic analysis of the Global Burden of Disease Study 2021. Lancet Rheumatol 2023;5:e316-e329.
 
2. Maharty DC, Hines SC, Brown RB. Chronic low back pain in adults: evaluation and management. Am Fam Physician 2024;109:233-244.
 
3. Dowell D, Ragan KR, Jones CM, et al. CDC clinical practice guideline for prescribing opioids for pain-United States, 2022. MMWR Recomm Rep 2022;71:1-95.
 
4. Sandbrink F, Murphy JL, Johansson M, et al. The use of opioids in the management of chronic pain: synopsis of the 2022 updated U.S. Department of Veterans Affairs and U.S. Department of Defense clinical practice guideline. Ann Intern Med 2023;176:388-397.
 
5. McLean KJ, Kruis NE, Weintraub E, et al. A mixed-method exploratory assessment of provider-based stigma of opioid use disorder (OUD) and support for medications for opioid use disorder (MOUD) in carceral settings. Harm Reduct J 2025;22:14.
 
6. Christian NJ, Baysinger A, Bottner R, et al. Hospital-based stigma practices towards individuals with opioid use disorder: a qualitative study in Austin, Texas. Am J Med Open 2025;14:100106.
 
7. Moyo P, Merlin JS, George M, et al. Association of opioid use disorder diagnosis with use of physical therapy and chiropractic care among chronic low back pain patients: a group-based trajectory analysis. J Pain 2024;25:742-754.
 
8. Heavey SC, Bleasdale J, Rosenfeld EA, et al. Collaborative care models to improve pain and reduce opioid use in primary care: a systematic review. J Gen Intern Med 2023;38:3021-3040.