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SMJ // Article

Case Report

Bilateral Leser-Trélat Sign Mirroring Lung Adenocarcinoma with Early Metastases to the Contralateral Lung

Authors: Constantin A. Dasanu MD, PhD, Doru T. Alexandrescu MD

Abstract

Abstract:We present a case featuring a unique overlap between the body areas involved by lung adenocarcinoma and the cutaneous paraneoplastic sign of Leser-Trélat. In our patient, the Leser-Trélat sign consisted of explosive multiple seborrheic keratoses in combination with acanthosis nigricans, representing a remarkable geometric skin projection of lung cancer which involved both the upper lobes. Our case suggests a unique interrelation between the paraneoplastic sign of Leser-Trélat and the tumor itself. The recognition of this phenomenon may contribute to an early diagnosis and prompt surgical treatment of occult cancers.

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References

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