Case Report

Bullosis Diabeticorum Associated with a Prediabetic State

Authors: Pablo R. Lopez MD, Stuart Leicht MD, Justin R. Sigmon BA, Landon Stigall BS


Abstract:Bullosis diabeticorum, or diabetic bullae, is a non-inflammatory blistering condition that is virtually diagnostic of diabetes. Diabetic bullae most often present as painless, tense, superficial bullae that occur in an acral distribution and commonly heal in 2–6 weeks without scarring, but complications such as secondary bacterial infection or hemorrhage may occur. The diagnosis of bullosis diabeticorum in a nondiabetic patient should prompt screening for diabetes. A case of recurrent bullae in a prediabetic patient is presented, with a review of the clinical features and significance of bullosis diabeticorum.

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References1.Lipsky BA, Baker PD, Ahroni JH. Diabetic bullae: 12 cases of a purportedly rare cutaneous disorder. Int J Dermatol 2000;39:196–200.LipskyBA]]BakerPD]]AhroniJHDiabetic bullae: 12 cases of a purportedly rare cutaneous disorder.Int J Dermatol200039196-2002.Aye M, Masson EA. Dermatological care of the diabetic foot. Am J Clin Dermatol 2002;3:463–474.AyeM]]MassonEADermatological care of the diabetic foot.Am J Clin Dermatol20023463-4743.Salpeter SR, Buckley NS, Kahn JA, et al. Meta-analysis: metformin treatment in persons at risk of diabetes mellitus. Am J Med 2008;121:149–157.SalpeterSR]]BuckleyNS]]KahnJA&etal;Meta-analysis: metformin treatment in persons at risk of diabetes mellitus.Am J Med2008121149-1574.Bolognia JL, Jorizzo JL, Rapini RP. Other Vesiculobullous Diseases, in Dermatology. Philadelphia, PA, Mosby, 2003, ed 1, pp 501–508.5.American Diabetes Association. Standards of medical care in diabetes—2008. Diabetes Care 2008;31(suppl 1):S12–S54.American Diabetes AssociationStandards of medical care in diabetes—2008.Diabetes Care200831S12-S54