Abstract

Significant palliation can be obtained in some patients with ovarian or uterine cancer using drug therapy, and should be tried when other modalities have failed. Gestational trophoblastic disease is curable with drugs, but requires skillful evaluation and management. The use of combination chemotherapy in cervical cancer and other advanced gynecologic cancers should be evaluated further. Chemotherapy as an adjunct to early treatment requires careful evaluation in controlled trials, and ultimately may improve the outlook for these patients.